The goal of the Program is to develop a more efficient and competitive research infrastructure at the University of Puerto Rico Medical Sciences Campus (UPR-MSC) to conduct translational studies in health disparities affecting the Puerto Rican population. Efforts will focus on establishing a comprehensive program structure that leverages current research infrastructure with the purpose of improving and stimulating multidisciplinary collaborations utilizing network resources developed by the RCMI Translational Research Network (RTRN).
Our specific aims are: (1) develop an efficient and agile research infrastructure to provide services that will facilitate the conduct of multidisciplinary collaborative research in health disparities;(2) target specific technical and health disparities areas for development and provide initial funding for research activities to support them;(3) promote the professional development of faculty, graduate students, and technical personnel working on these areas. Key activities include the Tanslational Proteomics Center, the Center for Translational Genomics in Health Disparities and Rare Disorders, the Infectious and Global Diseases Program, the Translational Neurosciences Program, the Center for Information Technologies and Telecommunications, and the Pilot Project Program. Required key activities Collaborations and Partneships, Professional Development, and Recruitment and Hiring and Evaluation, as well as the selected key activities will be overseen by the Administration Core. Recognizing the importance of partnerships to maximize research investments (NCRR Strategic Plan 2009-2013), we have established a unique and novel collaboration with the Puerto Rico Science, Technology and Research Trust (PRSTRT) to support research areas that enhance the UPR-MSC research capacity and also impact the economic development of Puerto Rico. Targeted areas include proteomics, pharmacogenomics, and bioinformatics. We are confident that the RCMI Program, with the collaboration of the PRSTRT can lead the proposed research efforts successfully.

Public Health Relevance

The RCMI Program is in a strong position to provide leadership and achieve greater levels of development by focusing on more efficient and high quality services using the most advanced technologies, the enhancement of multi-disciplinary collaborations taking advantage of the RTRN network, the encouragement of global health initiatives with Latin American and Ibero American countries, and the development of translational studies in the health disparities that affect the Puerto Rican population.

National Institute of Health (NIH)
Research Centers in Minority Institutions Award (G12)
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Study Section
Special Emphasis Panel (ZRR1)
Program Officer
Zhang, Xinzhi
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University of Puerto Rico Med Sciences
Schools of Medicine
San Juan
United States
Zip Code
Colon-López, Vivian; Quiñones-Avila, Valerie; Del Toro-Mejías, Lizbeth M et al. (2014) Oral HPV infection in a clinic-based sample of Hispanic men. BMC Oral Health 14:7
Torres, Roxana; Santos, Elvia; Orraca, Luis et al. (2014) Diet quality, social determinants, and weight status in Puerto Rican children aged 12 years. J Acad Nutr Diet 114:1230-5
Suárez, Erick; Soto-Salgado, Marievelisse; Moreno-Gorrín, Camille et al. (2014) Report of the 2013 University of Puerto Rico-MD Anderson Cancer Center Conference entitled "Research on cancer epidemiology: risk factors and control in the Caribbean basin". P R Health Sci J 33:34-6
De Mello, Walmor C (2014) Angiotensin (1-7) increases the potassium current and the resting potential of arterial myocytes from vascular resistance vessels of normal adult rats: Pathophysiological implications. J Am Soc Hypertens 8:14-20
Palacios, Cristina; Martin, Berdine R; McCabe, George P et al. (2014) Dietary calcium requirements do not differ between Mexican-American boys and girls. J Nutr 144:1167-73
Comer, Eamon; Beaudoin, Jennifer A; Kato, Nobutaka et al. (2014) Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents. J Med Chem 57:8496-502
Velázquez-Marrero, Cristina; Seale, Garrett E; Treistman, Steven N et al. (2014) Large conductance voltage- and Ca2+-gated potassium (BK) channel ?4 subunit influences sensitivity and tolerance to alcohol by altering its response to kinases. J Biol Chem 289:29261-72
López-López, L; Nieves-Plaza, M; Castro, M del R et al. (2014) Mitochondrial DNA damage is associated with damage accrual and disease duration in patients with systemic lupus erythematosus. Lupus 23:1133-41
Vega-Melendez, Giam S; Blagburn, Jonathan M; Blanco, Rosa E (2014) Ciliary neurotrophic factor and fibroblast growth factor increase the speed and number of regenerating axons after optic nerve injury in adult Rana pipiens. J Neurosci Res 92:13-23
Palacios, Cristina; Gonzalez, Lilliana (2014) Is vitamin D deficiency a major global public health problem? J Steroid Biochem Mol Biol 144 Pt A:138-45

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