Suzanne C. Segerstrom is an independent investigator (PhD, 1997) who has established a productive research program in personality, self-regulation, and physiology. The application proposes to protect a high level of research effort (80%) by releasing her from teaching, service, and administrative responsibilities. This support will facilitate an expansion of her research program in the interactions among self-regulation, physiology, well-being, and health in older adults. The application has three foci: (i) executive cognitive function and heart rate variability are predicted to covary with self-regulatory success, (ii) self-regulatory success across domains (e.g., control of repetitive thought, acquisition of social or status resources) is predicted to correlate with mental and physical health, and (iii) social resources will have disproportionate effects on health with increasing age, as predicted by socioemotional selectivity theory. Career development activities under the award will include didactic and experiential training in aging, longitudinal design and analysis, and the responsible conduct of research;collaborations with dedicated aging researchers in cognition, neuropsychology, immunology, neurology, and methodology;and spearheading special projects and meetings. Research activities will include analysis of the relationship between executive function and self- regulation in her existing R01-funded, longitudinal research with community-dwelling older adults (N = 150) and studies of self-regulation and health in the R01 sample, a cross-sectional study of younger and older women focusing on immunosenescence (N=76), a longitudinal follow-up in a study of middle-aged adults (N = 96) that began in 1994, and a longitudinal study of amyotrophic lateral sclerosis patients and caregivers (N = 266). Proposed studies illustrating future directions examine the role of goal selection and optimization in promoting psychological and physiological well-being in older women with pain and the role of self-regulation in socioemotional selectivity and the contributions of executive cognitive function and heart rate variability to this relationship in older adults. The University of Kentucky and the Department of Psychology provide a rich environment for the development of this work. It is expected that K02 support would allow Dr. Segerstrom to acquire additional expertise in cognition, physiology, and aging;produce and disseminate cutting-edge research in self-regulation, aging, and health;expand her grant portfolio to continue this line of research;and train PhD students in the conduct of this research.

Public Health Relevance

NARRATIVE Older adults'ability to control thoughts, emotions, and behaviors - that is, to self-regulate - is important for acquiring and maintaining resources such as social relationships as well as meeting other demands such as compliance with medical regimens. Understanding the underlying resources for self-regulation, such as cognitive function, as well as the psychological, social, and physical consequences of self-regulatory ability and success, is important for optimizing older adults'health and well-being.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Research Scientist Development Award - Research (K02)
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National Institute on Aging Initial Review Group (NIA)
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Nielsen, Lisbeth
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University of Kentucky
Schools of Arts and Sciences
United States
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Segerstrom, Suzanne C; Evans, Daniel R (2016) Happy all the time? Affect, resources, and time use. Emotion 16:941-4
Segerstrom, Suzanne C; Hardy, Jaime K; Evans, Daniel R et al. (2016) Briefly Assessing Repetitive Thought Dimensions: Valence, Purpose, and Total. Assessment 23:614-23
Segerstrom, Suzanne C; Geiger, Paul J; Combs, Hannah L et al. (2016) Time perspective and social preference in older and younger adults: Effects of self-regulatory fatigue. Psychol Aging 31:594-604
Arnberg, Filip K; Lekander, Mats; Morey, Jennifer N et al. (2016) Self-rated health and interleukin-6: Longitudinal relationships in older adults. Brain Behav Immun 54:226-32
Segerstrom, Suzanne C; Combs, Hannah L; Winning, Ashley et al. (2016) The happy survivor? Effects of differential mortality on life satisfaction in older age. Psychol Aging 31:340-5
Reed, Rebecca G; Greenberg, Richard N; Segerstrom, Suzanne C (2016) Cytomegalovirus serostatus, inflammation, and antibody response to influenza vaccination in older adults: The moderating effect of beta blockade. Brain Behav Immun :
Boggero, Ian A; Eisenlohr-Moul, Tory; Segerstrom, Suzanne C (2016) Task-switching ability protects against the adverse effects of pain on health: A longitudinal study of older adults. Br J Health Psychol 21:434-50
Segerstrom, Suzanne C; Geiger, Paul J; Boggero, Ian A et al. (2016) Endogenous Cortisol Exposure and Declarative Verbal Memory: A Longitudinal Study of Healthy Older Adults. Psychosom Med 78:182-91
Morey, Jennifer N; Boggero, Ian A; Scott, April B et al. (2015) Current Directions in Stress and Human Immune Function. Curr Opin Psychol 5:13-17
Segerstrom, Suzanne C; Eisenlohr-Moul, Tory A; Evans, Daniel R et al. (2015) Repetitive thought dimensions, psychological well-being, and perceived growth in older adults: a multilevel, prospective study. Anxiety Stress Coping 28:287-302

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