This proposal is for a five year K24 Mid-Career Development Award for patient-oriented research and mentoring for Anthony Harris MD, MPH. The proposal involves research and mentoring in the areas of antimicrobial resistance and hospital epidemiology. At present, he is the principal investigator on one NIH R01 and one CDC R01. During his eight years as a faculty member, he has published more than 70 manuscripts. He has mentored a number of PhD epidemiology students and infectious disease fellows to successful academic careers and has received a mentoring award from the Society of Healthcare Epidemiology of America. He is internationally recognized for his work in the areas of antimicrobial resistance and hospital epidemiology. Dr. Harris is requesting this award to dedicate 50% of his time to mentoring, writing new grants in the areas of infection control interventions aimed at decreasing the emergence of antimicrobial resistance and nosocomial infections, and taking coursework in clinical trials and randomized-cluster design that will improve his patient-oriented research. This award will allow him to decrease his administrative and clinical responsibilities to allow more protected time for mentoring and research. This award will help him achieve his long-term goals, which include: 1) decreasing the incidence of nosocomial infections and decrease the emergence of antimicrobial resistance 2) continuing to successfully obtain NIH R01 funding in the areas of antimicrobial resistance and hospital epidemiology 3) continuing to move his patient-oriented research towards intervention trials including randomized-cluster intervention trials 4) continuing to develop his mentoring skills to mentor trainees to successfully pursue academic clinical research careers.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
5K24AI079040-05
Application #
8416369
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Korpela, Jukka K
Project Start
2009-02-23
Project End
2014-01-31
Budget Start
2013-02-01
Budget End
2014-01-31
Support Year
5
Fiscal Year
2013
Total Cost
$180,005
Indirect Cost
$13,334
Name
University of Maryland Baltimore
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Rock, Clare; Thom, Kerri A; Masnick, Max et al. (2014) Frequency of Klebsiella pneumoniae carbapenemase (KPC)-producing and non-KPC-producing Klebsiella species contamination of healthcare workers and the environment. Infect Control Hosp Epidemiol 35:426-9
Hazen, Tracy H; Zhao, LiCheng; Sahl, Jason W et al. (2014) Characterization of Klebsiella sp. strain 10982, a colonizer of humans that contains novel antibiotic resistance alleles and exhibits genetic similarities to plant and clinical Klebsiella isolates. Antimicrob Agents Chemother 58:1879-88
Hess, Aaron S; Kleinberg, Michael; Sorkin, John D et al. (2014) Prior colonization is associated with increased risk of antibiotic-resistant Gram-negative bacteremia in cancer patients. Diagn Microbiol Infect Dis 79:73-6
Barnes, Sean L; Morgan, Daniel J; Harris, Anthony D et al. (2014) Preventing the transmission of multidrug-resistant organisms: modeling the relative importance of hand hygiene and environmental cleaning interventions. Infect Control Hosp Epidemiol 35:1156-62
Hazen, Tracy H; Zhao, LiCheng; Boutin, Mallory A et al. (2014) Comparative genomics of an IncA/C multidrug resistance plasmid from Escherichia coli and Klebsiella isolates from intensive care unit patients and the utility of whole-genome sequencing in health care settings. Antimicrob Agents Chemother 58:4814-25
Stafford, Kristen A; Boutin, Mallory; Evans, Scott R et al. (2014) Difficulties in demonstrating superiority of an antibiotic for multidrug-resistant bacteria in nonrandomized studies. Clin Infect Dis 59:1142-7
Johnson, J Kristie; Wilson, Lucy E; Zhao, Licheng et al. (2014) Point prevalence of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae in Maryland. Infect Control Hosp Epidemiol 35:443-5
Rock, Clare; Harris, Anthony D; Reich, Nicholas G et al. (2013) Is hand hygiene before putting on nonsterile gloves in the intensive care unit a waste of health care worker time?--a randomized controlled trial. Am J Infect Control 41:994-6
Dallman, Michael D; Liu, Xinggang; Harris, Anthony D et al. (2013) Changes in transfusion practice over time in the PICU. Pediatr Crit Care Med 14:843-50
Harris, Anthony D; Pineles, Lisa; Belton, Beverly et al. (2013) Universal glove and gown use and acquisition of antibiotic-resistant bacteria in the ICU: a randomized trial. JAMA 310:1571-80

Showing the most recent 10 out of 35 publications