Despite dramatically escalating HIV rates among African Americans, few African Americans in the US engage in HIV clinical research. The dearth of African American researchers has likely hindered development of effective measures to combat the epidemic in this population. The mentoring goal of this proposal is to increase the pool of researchers - especially African American investigators - who conduct HIV-related patient oriented research. The proposal outlines a plan to recruit and provide training and support to mentees as they advance to research independence. The research goals of this proposal are to examine several key factors that foster and maintain continued HIV transmission and racial disparities in HIV-related morbidity and mortality among African Americans. The proposed research will examine: 1) factors associated with late diagnosis among African Americans with heterosexually transmitted HIV infection and 2) virologic treatment failure's relationship to neighborhood- level poverty and public prescription drug insurance. The studies will build on my previous research concerning the epidemiology of heterosexually transmitted HIV infection and the importance of socioeconomic contextual factors in population HIV transmission among African Americans. Through the proposed studies and work with UNC Health Policy and Administration faculty, I propose to extend my research skills to include health outcomes and health policy. These studies will provide empiric data for development of future individual-level and community-level structural interventions to decrease HIV transmission among African Americans and decrease morbidity and mortality among HIV+ African Americans and others in the South and the rest of the nation.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
5K24HD059358-05
Application #
8320999
Study Section
Behavioral and Social Consequences of HIV/AIDS Study Section (BSCH)
Program Officer
Newcomer, Susan
Project Start
2008-09-01
Project End
2014-08-31
Budget Start
2012-09-01
Budget End
2014-08-31
Support Year
5
Fiscal Year
2012
Total Cost
$170,373
Indirect Cost
$12,271
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
White, Becky L; Walsh, Joan; Rayasam, Swati et al. (2015) What Makes Me Screen for HIV? Perceived Barriers and Facilitators to Conducting Recommended Routine HIV Testing among Primary Care Physicians in the Southeastern United States. J Int Assoc Provid AIDS Care 14:127-35
Jennings, Larissa; Rompalo, Anne M; Wang, Jing et al. (2015) Prevalence and correlates of knowledge of male partner HIV testing and serostatus among African-American women living in high poverty, high HIV prevalence communities (HPTN 064). AIDS Behav 19:291-301
Adimora, Adaora A; Ramirez, Catalina; Schoenbach, Victor J et al. (2014) Policies and politics that promote HIV infection in the Southern United States. AIDS 28:1393-7
Buchanan, Ashley L; Hudgens, Michael G; Cole, Stephen R et al. (2014) Worth the weight: using inverse probability weighted Cox models in AIDS research. AIDS Res Hum Retroviruses 30:1170-7
Adimora, Adaora A; Hughes, James P; Wang, Jing et al. (2014) Characteristics of multiple and concurrent partnerships among women at high risk for HIV infection. J Acquir Immune Defic Syndr 65:99-106
Howe, Chanelle J; Napravnik, Sonia; Cole, Stephen R et al. (2014) African American race and HIV virological suppression: beyond disparities in clinic attendance. Am J Epidemiol 179:1484-92
Howe, Chanelle J; Cole, Stephen R; Napravnik, Sonia et al. (2014) The role of at-risk alcohol/drug use and treatment in appointment attendance and virologic suppression among HIV(+) African Americans. AIDS Res Hum Retroviruses 30:233-40
Adimora, Adaora A; Schoenbach, Victor J; Taylor, Eboni M et al. (2013) Sex ratio, poverty, and concurrent partnerships among men and women in the United States: a multilevel analysis. Ann Epidemiol 23:716-9
Atashili, Julius; Adimora, Adaora A; Ndumbe, Peter M et al. (2012) High prevalence of cervical squamous intraepithelial lesions in women on antiretroviral therapy in Cameroon: Is targeted screening feasible? Cancer Epidemiol 36:263-9
Menezes, Prema; Miller, William C; Wohl, David A et al. (2011) Does HAART efficacy translate to effectiveness? Evidence for a trial effect. PLoS One 6:e21824

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