Despite dramatically escalating HIV rates among African Americans, few African Americans in the US engage in HIV clinical research. The dearth of African American researchers has likely hindered development of effective measures to combat the epidemic in this population. The mentoring goal of this proposal is to increase the pool of researchers - especially African American investigators - who conduct HIV-related patient oriented research. The proposal outlines a plan to recruit and provide training and support to mentees as they advance to research independence. The research goals of this proposal are to examine several key factors that foster and maintain continued HIV transmission and racial disparities in HIV-related morbidity and mortality among African Americans. The proposed research will examine: 1) factors associated with late diagnosis among African Americans with heterosexually transmitted HIV infection and 2) virologic treatment failure's relationship to neighborhood- level poverty and public prescription drug insurance. The studies will build on my previous research concerning the epidemiology of heterosexually transmitted HIV infection and the importance of socioeconomic contextual factors in population HIV transmission among African Americans. Through the proposed studies and work with UNC Health Policy and Administration faculty, I propose to extend my research skills to include health outcomes and health policy. These studies will provide empiric data for development of future individual-level and community-level structural interventions to decrease HIV transmission among African Americans and decrease morbidity and mortality among HIV+ African Americans and others in the South and the rest of the nation.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Midcareer Investigator Award in Patient-Oriented Research (K24)
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Study Section
Behavioral and Social Consequences of HIV/AIDS Study Section (BSCH)
Program Officer
Newcomer, Susan
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University of North Carolina Chapel Hill
Internal Medicine/Medicine
Schools of Medicine
Chapel Hill
United States
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Buchanan, Ashley L; Hudgens, Michael G; Cole, Stephen R et al. (2018) Generalizing Evidence from Randomized Trials using Inverse Probability of Sampling Weights. J R Stat Soc Ser A Stat Soc 181:1193-1209
Scheidell, Joy D; Lejuez, Carl W; Golin, Carol E et al. (2017) Patterns of Mood and Personality Factors and Associations With STI/HIV-Related Drug and Sex Risk Among African American Male Inmates. Subst Use Misuse 52:929-938
Ludema, Christina; Cole, Stephen R; Eron Jr, Joseph J et al. (2017) Health Insurance Type and Control of Hypertension Among US Women Living With and Without HIV Infection in the Women's Interagency HIV Study. Am J Hypertens 30:594-601
Khan, Maria R; El-Bassel, Nabila; Golin, Carol E et al. (2017) The Committed Intimate Partnerships of Incarcerated African-American Men: Implications for Sexual HIV Transmission Risk and Prevention Opportunities. Arch Sex Behav 46:2173-2185
Ludema, Christina; Cole, Stephen R; Eron Jr, Joseph J et al. (2016) Impact of Health Insurance, ADAP, and Income on HIV Viral Suppression Among US Women in the Women's Interagency HIV Study, 2006-2009. J Acquir Immune Defic Syndr 73:307-312
Cope, Anna B; Ramirez, Catalina; DeVellis, Robert F et al. (2016) Measuring Concurrency Attitudes: Development and Validation of a Vignette-Based Scale. PLoS One 11:e0163947
Sanchez, Diana M; Schoenbach, Victor J; Harvey, S Marie et al. (2016) Can Young Adults Accurately Report Sexual Partnership Dates? Factors Associated With Interpartner and Dyad Agreement. Sex Transm Dis 43:324-31
Sanchez, Diana M; Schoenbach, Victor J; Harvey, S Marie et al. (2016) Association of perceived partner non-monogamy with prevalent and incident sexual concurrency. Sex Transm Infect 92:266-71
Ludema, Christina; Doherty, Irene A; White, Becky L et al. (2015) Characteristics of African American Women and Their Partners With Perceived Concurrent Partnerships in 4 Rural Counties in the Southeastern U.S. Sex Transm Dis 42:498-504
Ludema, Christina; Doherty, Irene A; White, Becky L et al. (2015) Religiosity, spirituality, and HIV risk behaviors among African American women from four rural counties in the southeastern U.S. J Health Care Poor Underserved 26:168-81

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