The Specific Aims of this application for a Midcareer Investigator Award in Patient-Oriented Research are 1) to use innovative technologies to Improve measurement of functional outcomes and to deliver psychological interventions to youth with chronic pain, and 2) to provide the candidate protected time and resources necessary to mentor postdoctoral fellows and junior faculty members who are pursuing clinical Investigation in pediatric pain. The candidate's programmatic research has focused on developing innovative methods to assess and treat chronic pain, disability, and sleep problems. During the course of this award, the candidate will complete research studies using innovative technologies to improve measurement of pain and sleep in a novel longitudinal study of sleep-wake behaviors. She will develop new research to examine the efficacy of an internet family cognitive-behavioral intervention on improving functional outcomes in adolescents with chronic pain. The candidate has an established track record of providing mentorship to graduate students, postdoctoral fellows, and junior faculty in psychology and medicine. The increased time allotted by this award will give the candidate the opportunity to focus on training additional postdoctoral fellows and faculty. The Research Plan includes two projects: an NIH/NICHD RO1 """"""""Sleep-wake disturbances in adolescents with chronic pain,"""""""" and a new clinical trial of an internet delivered psychological treatment for chronic pain """"""""Effect of Web-based CBT on Objective Functional Outcomes in Youth with Chronic Pain."""""""" The Mentoring Plan for beginning clinical Investigators consists of supervised participation in the candidate's ongoing research;conduct of independent research;and experience in professional activities and achieving professional milestones. A formal didactic program is available to mentees through the Human Investigations Program at Oregon Health &Science University (OHSU), a NIH K30 program, with seminars on study design, randomized controlled trials, ethics/human subjects, grant writing, and advanced analytic approaches. OHSU provides an ideal setting for this award because of the established collaborations, commitment to patient-oriented research, and the presence of a strong Clinical Translational Research Center.

Public Health Relevance

The public health goals of the candidate's research program are to develop innovative treatments for youth with chronic pain and sleep problems that can improve the current standard of care and minimize long-term problems with pain and disability. In addition, the candidate seeks to train the next generation of patient-oriented researchers in this area.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
5K24HD060068-04
Application #
8118601
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Haverkos, Lynne
Project Start
2009-09-30
Project End
2014-07-31
Budget Start
2011-08-01
Budget End
2012-07-31
Support Year
4
Fiscal Year
2011
Total Cost
$145,123
Indirect Cost
Name
Seattle Children's Hospital
Department
Type
DUNS #
048682157
City
Seattle
State
WA
Country
United States
Zip Code
98105
Rosenbloom, Brittany N; Rabbitts, Jennifer A; Palermo, Tonya M (2017) A developmental perspective on the impact of chronic pain in late adolescence and early adulthood: implications for assessment and intervention. Pain 158:1629-1632
Lifland, Brooke E; Mangione-Smith, Rita; Palermo, Tonya M et al. (2017) Agreement between Parent Proxy- and Child Self-Report of Pain Intensity and Health-Related Quality of Life after Surgery. Acad Pediatr :
Rabbitts, Jennifer A; Aaron, Rachel V; Fisher, Emma et al. (2017) Long-Term Pain and Recovery After Major Pediatric Surgery: A Qualitative Study With Teens, Parents, and Perioperative Care Providers. J Pain 18:778-786
Rabbitts, Jennifer A; Zhou, Chuan; Narayanan, Arthi et al. (2017) Longitudinal and Temporal Associations Between Daily Pain and Sleep Patterns After Major Pediatric Surgery. J Pain 18:656-663
Groenewald, Cornelius B; Beals-Erickson, Sarah E; Ralston-Wilson, Jaime et al. (2017) Complementary and Alternative Medicine Use by Children With Pain in the United States. Acad Pediatr 17:785-793
Rabbitts, Jennifer A; Fisher, Emma; Rosenbloom, Brittany N et al. (2017) Prevalence and Predictors of Chronic Postsurgical Pain in Children: A Systematic Review and Meta-Analysis. J Pain 18:605-614
Palermo, Tonya M; Dudeney, Joanne; Santanelli, James P et al. (2017) Feasibility and Acceptability of Internet-delivered Cognitive Behavioral Therapy for Chronic Pain in Adolescents With Sickle Cell Disease and Their Parents. J Pediatr Hematol Oncol :
Lewandowski Holley, Amy; Wilson, Anna C; Cho, Elise et al. (2017) Clinical Phenotyping of Youth With New-Onset Musculoskeletal Pain: A Controlled Cohort Study. Clin J Pain 33:28-36
Rabbitts, Jennifer A; Aaron, Rachel V; Zempsky, William T et al. (2017) Validation of the Youth Acute Pain Functional Ability Questionnaire in Children and Adolescents Undergoing Inpatient Surgery. J Pain 18:1209-1215
Livingstone, Margaret J; Groenewald, Cornelius B; Rabbitts, Jennifer A et al. (2017) Codeine use among children in the United States: a nationally representative study from 1996 to 2013. Paediatr Anaesth 27:19-27

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