Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL043506-11
Application #
2221059
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1983-08-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Li, Shih-Hon; Gorlatova, Natalia V; Lawrence, Daniel A et al. (2008) Structural differences between active forms of plasminogen activator inhibitor type 1 revealed by conformationally sensitive ligands. J Biol Chem 283:18147-57
Barker-Carlson, Karen; Lawrence, Daniel A; Schwartz, Bradford S (2002) Acyl-enzyme complexes between tissue-type plasminogen activator and neuroserpin are short-lived in vitro. J Biol Chem 277:46852-7
Schwartz, B S; Espana, F (1999) Two distinct urokinase-serpin interactions regulate the initiation of cell surface-associated plasminogen activation. J Biol Chem 274:15278-83
Lumelsky, N L; Schwartz, B S (1997) Protein kinase C in erythroid and megakaryocytic differentiation: possible role in lineage determination. Biochim Biophys Acta 1358:79-92
Lumelsky, N L; Schwartz, B S (1996) Protease inhibitors induce specific changes in protein tyrosine phosphorylation that correlate with inhibition of apoptosis in myeloid cells. Cancer Res 56:3909-14
Goldman, I L; Kopelberg, M; Debaene, J E et al. (1996) Antiplatelet activity in onion (Allium cepa) is sulfur dependent. Thromb Haemost 76:450-2
Manchanda, N; Schwartz, B S (1995) Interaction of single-chain urokinase and plasminogen activator inhibitor type 1. J Biol Chem 270:20032-5
Schwartz, B S (1994) Differential inhibition of soluble and cell surface receptor-bound single-chain urokinase by plasminogen activator inhibitor type 2. A potential regulatory mechanism. J Biol Chem 269:8319-23
Schwartz, B S; Bradshaw, J D (1992) Regulation of plasminogen activator inhibitor mRNA levels in lipopolysaccharide-stimulated human monocytes. Correlation with production of the protein. J Biol Chem 267:7089-94
Manchanda, N; Schwartz, B S (1991) Single chain urokinase. Augmentation of enzymatic activity upon binding to monocytes. J Biol Chem 266:14580-4