This application, in response to RFA TR-12-006: """"""""Institutional Clinical and Translational Science Award (U54)"""""""", requests support for the University of Utah's Center for Clinical and Translational Science (CCTS). Our CCTS is built upon the UU's historic strengths in genetics and bioinformatics. Our vision for the next five years is to maintain and leverage the service cores of the CCTS and use that infrastructure as a springboard to launch new programs. With implementation of this vision we will fulfill the Aims of the CTSA described in the FOA by maintaining a home for translational research to: (1) Increase the quality, quantity, safety, efficiency, and impact of translational research for all conditions;(2) Provide resources and services to support and speed the planning and implementation of clinical and translational research across the entire range of research and communities;(3) Train, mentor, and support the next generation of translational investigators through the stage of becoming principal investigators and productive faculty members;(4) Maintain a governance structure that represents the full spectrum of translational science and all of its stakeholders to effectively fulfill the Aims;(5) Engage in a process of continuous evaluation, improvement, and innovation in all of these areas. The mission of the UU CCTS will be to provide support for all aspects of translational research. Even support that can be characterized as """"""""service"""""""" will be used to inform innovation and catalyze new thinking. In addition, we will direct new resources toward providing special expertise to the CTSA consortium in specific areas, namely: Human genetics;genotype/phenotype correlation;health services research including comparative effectiveness;medical device innovation, and;taking the electronic medical record to the next level as a tool for medical care and medical research. We will continue to perform research aimed at re-engineering the process of translational investigation.

Public Health Relevance

;- Providing resources and services to support and speed the planning and implementation of clinical and translational research across the entire range of research and communities.

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Mentored Career Development Award (KL2)
Project #
5KL2TR001065-02
Application #
8743323
Study Section
Special Emphasis Panel (ZAI1-PTM-C (S1))
Program Officer
Brazhnik, Olga
Project Start
2013-09-26
Project End
2018-04-30
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
2
Fiscal Year
2014
Total Cost
$242,600
Indirect Cost
$17,600
Name
University of Utah
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Kepka, Deanna; Spigarelli, Michael G; Warner, Echo L et al. (2016) Statewide analysis of missed opportunities for human papillomavirus vaccination using vaccine registry data. Papillomavirus Res 2:128-132
Theilen, Lauren H; Fraser, Alison; Hollingshaus, Michael S et al. (2016) All-Cause and Cause-Specific Mortality After Hypertensive Disease of Pregnancy. Obstet Gynecol 128:238-44
Graf, Erin H; Simmon, Keith E; Tardif, Keith D et al. (2016) Unbiased Detection of Respiratory Viruses by Use of RNA Sequencing-Based Metagenomics: a Systematic Comparison to a Commercial PCR Panel. J Clin Microbiol 54:1000-7
Lai, Djin; Bodson, Julia; Davis, France A et al. (2016) Diverse Families' Experiences with HPV Vaccine Information Sources: A Community-Based Participatory Approach. J Community Health :
Lai, Djin; Ding, Qian; Bodson, Julia et al. (2016) Factors Associated with Increased HPV Vaccine Use in Rural-Frontier U.S. States. Public Health Nurs 33:283-94
Byington, Carrie L; Keenan, Heather; Phillips, John D et al. (2016) A Matrix Mentoring Model That Effectively Supports Clinical and Translational Scientists and Increases Inclusion in Biomedical Research: Lessons From the University of Utah. Acad Med 91:497-502
Flygare, Steven; Simmon, Keith; Miller, Chase et al. (2016) Taxonomer: an interactive metagenomics analysis portal for universal pathogen detection and host mRNA expression profiling. Genome Biol 17:111
Garrido, Carolina; Spivak, Adam M; Soriano-Sarabia, Natalia et al. (2016) HIV Latency-Reversing Agents Have Diverse Effects on Natural Killer Cell Function. Front Immunol 7:356
Pulsipher, Abigail; Qin, Xuan; Thomas, Andrew J et al. (2016) Prevention of sinonasal inflammation by a synthetic glycosaminoglycan. Int Forum Allergy Rhinol :
Spivak, Adam M; Planelles, Vicente (2016) HIV-1 Eradication: Early Trials (and Tribulations). Trends Mol Med 22:10-27

Showing the most recent 10 out of 17 publications