This application, in response to RFA TR-12-006: """"""""Institutional Clinical and Translational Science Award (U54)"""""""", requests support for the University of Utah's Center for Clinical and Translational Science (CCTS). Our CCTS is built upon the UU's historic strengths in genetics and bioinformatics. Our vision for the next five years is to maintain and leverage the service cores of the CCTS and use that infrastructure as a springboard to launch new programs. With implementation of this vision we will fulfill the Aims of the CTSA described in the FOA by maintaining a home for translational research to: (1) Increase the quality, quantity, safety, efficiency, and impact of translational research for all conditions;(2) Provide resources and services to support and speed the planning and implementation of clinical and translational research across the entire range of research and communities;(3) Train, mentor, and support the next generation of translational investigators through the stage of becoming principal investigators and productive faculty members;(4) Maintain a governance structure that represents the full spectrum of translational science and all of its stakeholders to effectively fulfill the Aims;(5) Engage in a process of continuous evaluation, improvement, and innovation in all of these areas. The mission of the UU CCTS will be to provide support for all aspects of translational research. Even support that can be characterized as """"""""service"""""""" will be used to inform innovation and catalyze new thinking. In addition, we will direct new resources toward providing special expertise to the CTSA consortium in specific areas, namely: Human genetics;genotype/phenotype correlation;health services research including comparative effectiveness;medical device innovation, and;taking the electronic medical record to the next level as a tool for medical care and medical research. We will continue to perform research aimed at re-engineering the process of translational investigation.

Public Health Relevance

;- Providing resources and services to support and speed the planning and implementation of clinical and translational research across the entire range of research and communities.

National Institute of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
Mentored Career Development Award (KL2)
Project #
Application #
Study Section
Special Emphasis Panel (ZAI1-PTM-C (S1))
Program Officer
Brazhnik, Olga
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Utah
Internal Medicine/Medicine
Schools of Medicine
Salt Lake City
United States
Zip Code
Wise, Sarah K; Lin, Sandra Y; Toskala, Elina et al. (2018) International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis. Int Forum Allergy Rhinol 8:108-352
Falconer, Jonathan L; Alt, Jeremiah A; Grainger, David W (2018) Comparing ex vivo and in vitro translocation of silver nanoparticles and ions through human nasal epithelium. Biomaterials 171:97-106
Pulsipher, Abigail; Davis, Brock M; Smith, Kristine A et al. (2018) Calgranulin C (S100A12) Is Differentially Expressed in Subtypes of Chronic Rhinosinusitis. Am J Rhinol Allergy 32:380-387
Smith, Kristine A; Ashby, Shaelene; Orlandi, Richard R et al. (2018) The price of pain in chronic rhinosinusitis. Int Forum Allergy Rhinol :
Smith, Kristine A; Pulsipher, Abigail; Gabrielsen, David A et al. (2018) Biologics in Chronic Rhinosinusitis: An Update and Thoughts for Future Directions. Am J Rhinol Allergy 32:412-423
Monroe, Marcus M; Hashibe, Mia; Orb, Quinn et al. (2018) Familial clustering of oropharyngeal squamous cell carcinoma in the Utah population. Head Neck 40:384-393
Smith, Kristine A; Orlandi, Richard R; Oakley, Gretchen et al. (2018) Long-term revision rates for endoscopic sinus surgery. Int Forum Allergy Rhinol :
Alt, Jeremiah A; Lee, Won Yong; Davis, Brock M et al. (2018) A synthetic glycosaminoglycan reduces sinonasal inflammation in a murine model of chronic rhinosinusitis. PLoS One 13:e0204709
Quinn, Nicholas A; Alt, Jeremiah A; Ashby, Shaelene et al. (2018) Time, Resident Involvement, and Supply Drive Cost Variability in Septoplasty with Turbinate Reduction. Otolaryngol Head Neck Surg 159:310-314
Reynolds, Megan M; Avendano, Mauricio (2018) Social Policy Expenditures and Life Expectancy in High-Income Countries. Am J Prev Med 54:72-79

Showing the most recent 10 out of 104 publications