The Biostatistics and Data Management Core (BDMC Core B) of the MPD Research Consortium (MPD-RC) provides, statistical collaboration and data rnanagement and operations, support for .MPD-RC investigator initiated research and clinical projects through the combined expertises of the integrated Cores at NYU School of.Medicine (Judith D. Goldberg,Sc.D.) and the Consorzio Mario Negri Sud (Robterto Marchioli, M.D.). The collaboration allpvys .the integration of alMaboratpry.and clinjcal study data into the MPD-RC central database for integ rated, statistical analysis. In particular, state of the art statistical collaboration is provided forthe design, conduct, and analysis of translational research including clinical trials and laboratory studies to further the understanding of the causes and treatment of myelofibrosis and polycythemia vera. The Data Management component of the Core provides on line database and data entry systems and procedures and an infrastructure to facilitate communication among investigators and to facilitate the conduct of multicenter clinical and translational studies in these disease.
The Biostatistics and Data Management Core of the MPD-RC provides collaboration in all phases of the research projects from study design through reporting to obtain meanlngful results from the multiple MPDRC research projects and programs using minimal patieint and animal resources. The user friendly web-based data management system facilitates data collection and management and collaborations across an international network of investigators conducting multicenter clinical trials and research programs.
|Wang, Xiaoli; Cho, Sool Yeon; Hu, Cing Siang et al. (2015) C-X-C motif chemokine 12 influences the development of extramedullary hematopoiesis in the spleens of myelofibrosis patients. Exp Hematol 43:100-9.e1|
|Wehrle, Julius; Pahl, Heike L; von Bubnoff, Nikolas (2014) Ponatinib: a third-generation inhibitor for the treatment of CML. Recent Results Cancer Res 201:99-107|
|Spivak, Jerry L; Considine, Michael; Williams, Donna M et al. (2014) Two clinical phenotypes in polycythemia vera. N Engl J Med 371:808-17|
|Dickinson, Rachel E; Milne, Paul; Jardine, Laura et al. (2014) The evolution of cellular deficiency in GATA2 mutation. Blood 123:863-74|
|Rondelli, Damiano; Goldberg, Judith D; Isola, Luis et al. (2014) MPD-RC 101 prospective study of reduced-intensity allogeneic hematopoietic stem cell transplantation in patients with myelofibrosis. Blood 124:1183-91|
|Rheinemann, Lara; Seeger, Thalia S; Wehrle, Julius et al. (2014) NFE2 regulates transcription of multiple enzymes in the heme biosynthesis pathway. Haematologica 99:e208-10|
|Kapralova, Katarina; Lanikova, Lucie; Lorenzo, Felipe et al. (2014) RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling. Blood 123:391-4|
|Wang, L; Swierczek, S I; Drummond, J et al. (2014) Whole-exome sequencing of polycythemia vera revealed novel driver genes and somatic mutation shared by T cells and granulocytes. Leukemia 28:935-8|
|Ye, Zhaohui; Liu, Cyndi F; Lanikova, Lucie et al. (2014) Differential sensitivity to JAK inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient-specific induced pluripotent stem cells. Stem Cells 32:269-78|
|Essig, Aitomi; Duque-Afonso, Jesus; Schwemmers, Sven et al. (2014) The AML1/ETO target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells. Leuk Res 38:340-5|
Showing the most recent 10 out of 116 publications