Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
3P01GM039546-06S1
Application #
3096300
Study Section
Special Emphasis Panel (SRC)
Project Start
1987-09-01
Project End
1997-08-31
Budget Start
1993-05-01
Budget End
1993-08-31
Support Year
6
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Arts and Sciences
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Riley, Kasandra J; Steitz, Joan A (2013) The ""Observer Effect"" in genome-wide surveys of protein-RNA interactions. Mol Cell 49:601-4
Brautigam, C A; Aschheim, K; Steitz, T A (1999) Structural elucidation of the binding and inhibitory properties of lanthanide (III) ions at the 3'-5' exonucleolytic active site of the Klenow fragment. Chem Biol 6:901-8
Ota, N; Stroupe, C; Ferreira-da-Silva, J M et al. (1999) Non-Boltzmann thermodynamic integration (NBTI) for macromolecular systems: relative free energy of binding of trypsin to benzamidine and benzylamine. Proteins 37:641-53
Friedman, J M (1999) Interconversion between 3D molecular representations: some macromolecular applications of spherical harmonic-Bessel expansions about an arbitrary center. Comput Chem 23:9-23
Ippolito, J A; Steitz, T A (1998) A 1.3-A resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation. Proc Natl Acad Sci U S A 95:9819-24
Jaeger, J; Restle, T; Steitz, T A (1998) The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor. EMBO J 17:4535-42
Brautigam, C A; Steitz, T A (1998) Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates. J Mol Biol 277:363-77
Friedman, J M (1997) Fourier-filtered van der Waals contact surfaces: accurate ligand shapes from protein structures. Protein Eng 10:851-63
Mishima, Y; Steitz, J A (1995) Site-specific crosslinking of 4-thiouridine-modified human tRNA(3Lys) to reverse transcriptase from human immunodeficiency virus type I. EMBO J 14:2679-87
Long, K S; Crothers, D M (1995) Interaction of human immunodeficiency virus type 1 Tat-derived peptides with TAR RNA. Biochemistry 34:8885-95

Showing the most recent 10 out of 42 publications