Objective: The purpose of the administrative core is to provide programmatic direction, promote interaction among the investigators and provide administrative budget management. Description: Dr. Ginsberg and Justin Maisonet's offices are located in the same laboratory suite. Mr. Maisonet occupies a work station adjacent to Dr. Ginsberg. The program will require extensive interactions between the participants, as well as access to the central UCSD electronic mail system and central computing facilities. It will be the responsibility of the administrative core to coordinate the monitoring of scientific progress, facilitate scientific dialogue between investigators, assure the fiscal resources are optimally utilized, and to provide access to the computerized databases and Ethernet computer network. The Core will also maintain records for an extensive (>2000 element) DNA library and cell line (>100 lines) collection.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL078784-10
Application #
8666026
Study Section
Heart, Lung, and Blood Program Project Review Committee (HLBP)
Project Start
Project End
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
10
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Klann, Jane E; Kim, Stephanie H; Remedios, Kelly A et al. (2018) Integrin Activation Controls Regulatory T Cell-Mediated Peripheral Tolerance. J Immunol 200:4012-4023
Weijts, Bart; Gutierrez, Edgar; Saikin, Semion K et al. (2018) Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos. Nat Commun 9:5314
Sun, Hao; Lagarrigue, Frederic; Gingras, Alexandre R et al. (2018) Transmission of integrin ?7 transmembrane domain topology enables gut lymphoid tissue development. J Cell Biol 217:1453-1465
Marki, Alex; Buscher, Konrad; Mikulski, Zbigniew et al. (2018) Rolling neutrophils form tethers and slings under physiologic conditions in vivo. J Leukoc Biol 103:67-70
Moccetti, Federico; Brown, Eran; Xie, Aris et al. (2018) Myocardial Infarction Produces Sustained Proinflammatory Endothelial Activation in Remote Arteries. J Am Coll Cardiol 72:1015-1026
Lagarrigue, Frederic; Gingras, Alexandre R; Paul, David S et al. (2018) Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation. Blood Adv 2:2358-2368
Wolf, Dennis; Anto-Michel, Nathaly; Blankenbach, Hermann et al. (2018) A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense. Nat Commun 9:525
Rothmeier, Andrea S; Marchese, Patrizia; Langer, Florian et al. (2017) Tissue Factor Prothrombotic Activity Is Regulated by Integrin-arf6 Trafficking. Arterioscler Thromb Vasc Biol 37:1323-1331
Baumer, Yvonne; McCurdy, Sara; Alcala, Martin et al. (2017) CD98 regulates vascular smooth muscle cell proliferation in atherosclerosis. Atherosclerosis 256:105-114
Liao, Zhongji; Kasirer-Friede, Ana; Shattil, Sanford J (2017) Optogenetic interrogation of integrin ?V?3 function in endothelial cells. J Cell Sci 130:3532-3541

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