of Core Unit Dr. Young will be responsible for the day-to-day operation of this Program Project Grant, with frequent consultations with Drs. Reue, Tontonoz, and Fong. The Administrative Core has been organized to assist the Principal Investigators in this task. An administrative assistant, Ms. Sandy Chang, is located adjacent to Dr. Young's office in the MacDonald Research Laboratories Building. The three major functions of the Administrative Core are: ? Administrative: This includes non-routine functions that require organizational skills and initiative, such as daily supervision of clerical and accounting functions, translating the decisions of the Project and Core Leaders into action, without an undue expenditure of the investigators'time. This often requires considerable communication and logistics skills on the part of the administrative assistant (e.g., to make all of the administrative decisions to redirect funds or effort, and to make sure that all PPG personnel affected by a decision understand the administrative changes). The administrative assistant will work on scheduling and notification for the weekly PPG meeting, and will provide assistance with travel arrangements and reimbursement of expenses. The administrative assistant will also provide notification of due dates for the Animal Research Committee and the Radiation and Biosafety Offices. The administrative assistant will also establish and maintain a central filing system and schedule seminars. ? Clerical: The Project and Core Leaders end up doing more than 95% of the word processing, but advanced word processing and record-keeping skills are required to keep the PPG functioning smoothly. Examples include formatting reports and manuscripts, preparing bibliographies, and typing memos and letters of collaboration. It is important that a competent administrative assistant oversee and participate in these routine operations and provide the discipline and continuity required for a successful PPG. The administrative assistant will assist with the final formatting of manuscripts and with the annual reports for the External Advisory Board and for the NIH (both scientific and financial). ? Accounting: Accurate and prompt accounting is essential for the financial health of the PPG. All personnel matters for the staff of the PPG are coordinated by the administrative assistant, including hiring, merit increases, and termination of PPG employees. In addition, the Administrative Core is responsible for ordering and receiving all supplies purchased for the cores and projects located at UCLA. The administrative assistant will record orders from the Projects and Cores, and then order supplies from the appropriate vendors. The assistant will also track and record the delivery of the orders, returning supplies that are incorrect or damaged. He/she will also set up and maintain ledgers in accord with university accounting procedures and prepare monthly status reports for the Project and Core Leaders.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL090553-05
Application #
8378636
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
2013-12-14
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
5
Fiscal Year
2012
Total Cost
$461,250
Indirect Cost
$139,920
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Arnold, Arthur P; Reue, Karen; Eghbali, Mansoureh et al. (2016) The importance of having two X chromosomes. Philos Trans R Soc Lond B Biol Sci 371:20150113
Tian, Xiao Yu; Ganeshan, Kirthana; Hong, Cynthia et al. (2016) Thermoneutral Housing Accelerates Metabolic Inflammation to Potentiate Atherosclerosis but Not Insulin Resistance. Cell Metab 23:165-78
Wang, Bo; Rong, Xin; Duerr, Mark A et al. (2016) Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet. Cell Metab 23:492-504
Allan, Christopher M; Procaccia, Shiri; Tran, Deanna et al. (2016) Palmoplantar Keratoderma in Slurp2-Deficient Mice. J Invest Dermatol 136:436-43
Dijk, Wieneke; Beigneux, Anne P; Larsson, Mikael et al. (2016) Angiopoietin-like 4 promotes intracellular degradation of lipoprotein lipase in adipocytes. J Lipid Res 57:1670-83
Ribas, Vicent; Drew, Brian G; Zhou, Zhenqi et al. (2016) Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Sci Transl Med 8:334ra54
Mysling, Simon; Kristensen, Kristian Kølby; Larsson, Mikael et al. (2016) The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding. Elife 5:
Mysling, Simon; Kristensen, Kristian Kølby; Larsson, Mikael et al. (2016) The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain. Elife 5:e12095
Vergnes, Laurent; Chin, Robert G; de Aguiar Vallim, Thomas et al. (2016) SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression. J Lipid Res 57:410-21
Allan, Christopher M; Larsson, Mikael; Hu, Xuchen et al. (2016) An LPL-specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1. J Lipid Res 57:1889-1898

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