The Core has two main objectives: a) to provide Program investigators with cystic fibrosis (CF) and non-CF pigs and b) to help Program investigators successfully accomplish the aims of their projects. The Core will have the facilities and personnel to ensure the production of an adequate number of animals to meet the needs of the four Projects. Drs. Kim Brogden and Michael Welsh will codirect the Animal Models Core; their complementary skills and experience will ensure its success. In addition, we have assembled a group of colleagues and consultants who will be able to help us with any unanticipated developments.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL091842-05
Application #
8381596
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
2013-07-31
Budget Start
2012-08-01
Budget End
2013-07-31
Support Year
5
Fiscal Year
2012
Total Cost
$682,192
Indirect Cost
$222,266
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
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Ramsey, Bonnie W; Welsh, Michael J (2017) AJRCCM: 100-Year Anniversary. Progress along the Pathway of Discovery Leading to Treatment and Cure of Cystic Fibrosis. Am J Respir Crit Care Med 195:1092-1099
Vargas Buonfiglio, Luis G; Mudunkotuwa, Imali A; Abou Alaiwa, Mahmoud H et al. (2017) Effects of Coal Fly Ash Particulate Matter on the Antimicrobial Activity of Airway Surface Liquid. Environ Health Perspect 125:077003
Cooney, Ashley L; Abou Alaiwa, Mahmoud H; Shah, Viral S et al. (2016) Lentiviral-mediated phenotypic correction of cystic fibrosis pigs. JCI Insight 1:

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