Glycosciences Skills Development is a key component of the Lung Inflammatory Disease Program of Excellence in Glycoscience (LID-PEG). Four postdoctoral fellows will be designated as Skills Development Trainees with terms of 3-4 years. At any time, one Skills Development Trainee will be associated with (and supported by) each Project. Training will consist of three components: (1) Site-specific courses in glycobiology - With the assumption that glycobiology training is often modest at the doctoral and pre-doctoral levels, Skills Development Trainees will enroll in site-specific courses in the fundamentals of glycobiology. These opportunities will include "Essentials of Glycobiology" (at UCSD for trainees at Scripps), "Advanced Topics in Glycobiology" (at University of Georgia for trainees at the CCRC) and a newly created graduate-level course on Glycobiology directed by Dr. Schnaar (for trainees at Johns Hopkins). (2) Annual Skills Development Retreats - Each year all Skills Development Trainees will travel to one of the three Program sites (in rotation) for hands-on training. This will provide specialized experiences in glycoconjugate purification, analysis, chemistry and function. In addition, it will provide opportunities for every trainee to visit and network with glycoscientists at three of the major glycobiology centers in the US. (3) Enrichment and networking opportunities. Each site provides exanded opportunities for informal glycoscience training through specialized glycobiology seminar series and local or regional glycobiology interest groups. In addition, all trainees will attend the annual Society for Glycobiology meeting, the Glycobiology Gordon Conference, or other international or specialized meetings in the glycosciences.
Building an ongoing infrastructure capable of applying glycosciences to discovery and therapeutic development relevant to the mission of the NHLBI will require the training of the next generation of leaders in the field.
|Stowell, Sean R; Arthur, Connie M; McBride, Ryan et al. (2014) Microbial glycan microarrays define key features of host-microbial interactions. Nat Chem Biol 10:470-6|
|Kawasaki, Norihito; Rillahan, Cory D; Cheng, Tan-Yun et al. (2014) Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation. J Immunol 193:1560-6|
|Kiwamoto, Takumi; Brummet, Mary E; Wu, Fan et al. (2014) Mice deficient in the St3gal3 gene product *2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation. J Allergy Clin Immunol 133:240-7.e1-3|
|Macauley, Matthew S; Crocker, Paul R; Paulson, James C (2014) Siglec-mediated regulation of immune cell function in disease. Nat Rev Immunol 14:653-66|
|Cho, Seok Hyun; Oh, Sun Young; Lane, Andrew P et al. (2014) Regulation of nasal airway homeostasis and inflammation in mice by SHP-1 and Th2/Th1 signaling pathways. PLoS One 9:e103685|
|Fang, Ping; Zhou, Li; Zhou, Yuqi et al. (2014) Immune modulatory effects of IL-22 on allergen-induced pulmonary inflammation. PLoS One 9:e107454|
|Nix, David B; Kumagai, Tadahiro; Katoh, Toshihiko et al. (2014) Improved in-gel reductive ?-elimination for comprehensive O-linked and sulfo-glycomics by mass spectrometry. J Vis Exp :e51840|
|Rillahan, Cory D; Macauley, Matthew S; Schwartz, Erik et al. (2014) Disubstituted Sialic Acid Ligands Targeting Siglecs CD33 and CD22 Associated with Myeloid Leukaemias and B Cell Lymphomas. Chem Sci 5:2398-2406|
|Kiwamoto, Takumi; Katoh, Toshihiko; Tiemeyer, Michael et al. (2013) The role of lung epithelial ligands for Siglec-8 and Siglec-F in eosinophilic inflammation. Curr Opin Allergy Clin Immunol 13:106-11|
|Rillahan, Cory D; Schwartz, Erik; Rademacher, Christoph et al. (2013) On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7. ACS Chem Biol 8:1417-22|
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