During the past 20 years, studies on HIV and AIDS pathogenesis conducted at UCLA have relied on a wellrun, state-of-the-art virology core facility. The overall purpose of this facility has been to serve as an accessible resource for development of research techniques for UCLA investigators pursuing basic science, clinical science and behavioral science research in the field of HIV/AIDS. Throughout its existence the goals of the Virology Core have reflected the scientific needs of its users. Uniquely suited to the UCLA community, the Virology Core provides resources that are not easily obtainable commercially nor does it replace existing resources normally supported by individual research grants. To insure that the Virology/BSL3 Tissue Culture Core will continue to be an integral component of the UCLA CFAR/AIDS Institute, the following specific aims are proposed: 1. 1. To supply a readily available resource for UCLA investigators requiring virological support in the form of assays, technical expertise and storage/maintenance of viral specimen inventories for investigators; 2. To provide access and appropriate training for use of the Core-maintained biosafety level 3 (BSL3) tissue culture facility; 3. To serve as a """"""""wet lab"""""""" resource for behavioral and social science HIV investigators, offering access to routine bioassays and virological assessments. 4. To develop, evaluate and incorporate new procedures and assays relevant to the needs of UCLA HIV/AIDS investigators; 5. To foster collaboration among UCLA HIV/AIDS investigators, encourage the development of junior investigators and solicit the participation of established investigators not currently working in HIV/AIDS. 6. To offer training and expertise for international investigators and their laboratories who are pursuing collaborative ventures with UCLA faculty.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Center Core Grants (P30)
Project #
5P30AI028697-22
Application #
8230852
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2011-03-01
Budget End
2012-02-29
Support Year
22
Fiscal Year
2011
Total Cost
$182,574
Indirect Cost
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Lowe, Emily; Truscott, Laurel C; De Oliveira, Satiro N (2016) In Vitro Generation of Human NK Cells Expressing Chimeric Antigen Receptor Through Differentiation of Gene-Modified Hematopoietic Stem Cells. Methods Mol Biol 1441:241-51
Epeldegui, Marta; Lee, Jeannette Y; Martínez, Anna C et al. (2016) Predictive Value of Cytokines and Immune Activation Biomarkers in AIDS-Related Non-Hodgkin Lymphoma Treated with Rituximab plus Infusional EPOCH (AMC-034 trial). Clin Cancer Res 22:328-36
Lake, Jordan E; Popov, Mikhail; Post, Wendy S et al. (2016) Visceral fat is associated with brain structure independent of human immunodeficiency virus infection status. J Neurovirol :
Peckham-Gregory, Erin C; Thapa, Dharma R; Martinson, Jeremy et al. (2016) MicroRNA-related polymorphisms and non-Hodgkin lymphoma susceptibility in the Multicenter AIDS Cohort Study. Cancer Epidemiol 45:47-57
Tsai, Alexander C; Tomlinson, Mark; Comulada, W Scott et al. (2016) Food insufficiency, depression, and the modifying role of social support: Evidence from a population-based, prospective cohort of pregnant women in peri-urban South Africa. Soc Sci Med 151:69-77
Tsai, Alexander C; Tomlinson, Mark; Comulada, W Scott et al. (2016) Intimate Partner Violence and Depression Symptom Severity among South African Women during Pregnancy and Postpartum: Population-Based Prospective Cohort Study. PLoS Med 13:e1001943
Shimizu, Saki; Yadav, Swati Seth; An, Dong Sung (2016) Stable Delivery of CCR5-Directed shRNA into Human Primary Peripheral Blood Mononuclear Cells and Hematopoietic Stem/Progenitor Cells via a Lentiviral Vector. Methods Mol Biol 1364:235-48
Deng, Yun; Zhao, Jian; Sakurai, Daisuke et al. (2016) Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production. Ann Rheum Dis 75:2007-2013
Liu, Sandy; Cadaneanu, Radu M; Zhang, Baohui et al. (2016) Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone. PLoS One 11:e0163232
Ramirez, Christina M; Sinclair, Elizabeth; Epling, Lorrie et al. (2016) Immunologic profiles distinguish aviremic HIV-infected adults. AIDS 30:1553-62

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