The Purdue University Center for Cancer Research Mass Spectrometry Shared Resource is part of the Purdue University Campus-wide Mass Spectrometry Center (CWMSC) and is operated under the Purdue University chargeback system. The Shared Resource has provided essential services for members of the Cancer Center for over twenty-five years and this service reflects the strength and national leadership of Purdue University in analytical chemistry. The Mass Spectrometry Shared Resource provides analysis services for small organic compounds that are mainly generated in the Medicinal Chemistry and Drug Delivery and Molecular Sensing scientific programs. The Shared Resource offers a full range of mass spectrometry ionization techniques including Electrospray Ionization (ESI), Matrix-Assisted Laser Desorption Ionization (MALDI) and Atmospheric Pressure Chemical Ionization (APCI) for the analysis of nonvolatile components. Electron Impact (El) and Chemical Ionization (Cl) for volatile components, Inductively Coupled Argon Plasma Ionization (ICP) for multi-element analysis and High Resolution Mass Measurement capabilities.

Public Health Relevance

The role of the shared resource is to assist individual investigators and scientific Programs within the Center that are seeking novel approaches to addressing a variety of cancer-related issues. In offering these key services, the shared resource provides the expertise necessary for achieving the next challenge;challenges that when solved will aid in reducing the pain and suffering of cancer.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA023168-34
Application #
8681165
Study Section
Subcommittee B - Comprehensiveness (NCI)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
34
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Purdue University
Department
Type
DUNS #
City
West Lafayette
State
IN
Country
United States
Zip Code
47907
Zhou, Wenqing; Pal, Arpita S; Hsu, Alan Yi-Hui et al. (2018) MicroRNA-223 Suppresses the Canonical NF-?B Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation. Cell Rep 22:1810-1823
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Zhang, Zhuangzhuang; Cheng, Lijun; Li, Jie et al. (2018) Inhibition of the Wnt/?-Catenin Pathway Overcomes Resistance to Enzalutamide in Castration-Resistant Prostate Cancer. Cancer Res 78:3147-3162
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