Regional Pilot and Feasibility Study Grants Program The specific aim of the Michigan Diabetes Research Center (MDRC) expanded Pilot/Feasibility Study (P/FS) Grants Program is to stimulate new research and collaboration in the areas of diabetes, its complications and related endocrine and metabolic disorders in the region. This research may be in areas of basic biomedical science or clinical research. This program will fund at least 2 P/FS grants submitted by investigators from our three regional partners per year. A minimum of $80,000 per year will be provided by the MDRC and an additional $20,000 per year will be provided through cost-sharing agreements with the University of Toledo, Michigan State University, and Wayne State University. Each year, the MDRC will solicit applications for grants from full-time instructional or research faculty at these three institutions. Those eligible include: 1) new investigators without current or past NIH research support who are beginning careers in diabetes research, 2) established investigators new to diabetes research who wish to focus their expertise on diabetes, and 3) established investigators who propose innovative research in diabetes that represents a clear departure from their ongoing research. Applications are peer-reviewed by at least two extramural investigators with expertise in the area of the application. Those with merit, as judged by this review process and the Grants Program Advisory Council which includes representatives from the three regional partner universities, will receive P/FS awards. The ultimate goal of the grant program is to enhance communication and collaboration among regional diabetes researchers, accelerate the pace of research, and enable awardees to generate sufficient preliminary data for successful applications for major research funding from the NIH or other national granting agencies.

Public Health Relevance

This program attracts new investigators from diverse schools, departments, and institutes at the University of Toledo, Michigan State University, and Wayne State University into diabetes research;provides them with support and resources to successfully launch their research careers;and stimulates new, innovative, interdisciplinary and collaborative research with UM and regional investigators to accelerate the pace of discovery to prevent, treat, and ultimately cure diabetes and its complications.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK020572-36
Application #
8452526
Study Section
Special Emphasis Panel (ZDK1-GRB-S (O2))
Project Start
Project End
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
36
Fiscal Year
2013
Total Cost
$136,930
Indirect Cost
$48,872
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Yu, Jingcheng; Koenig, Ronald J (2018) Thyroid-Specific PPAR? Deletion Is Benign in the Mouse. Endocrinology 159:1463-1468
Griffin, Cameron; Eter, Leila; Lanzetta, Nico et al. (2018) TLR4, TRIF, and MyD88 are essential for myelopoiesis and CD11c+ adipose tissue macrophage production in obese mice. J Biol Chem 293:8775-8786
Jun, Goo; Manning, Alisa; Almeida, Marcio et al. (2018) Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees. Proc Natl Acad Sci U S A 115:379-384
Perkins, Bruce A; Lovblom, Leif E; Bril, Vera et al. (2018) Corneal confocal microscopy for identification of diabetic sensorimotor polyneuropathy: a pooled multinational consortium study. Diabetologia 61:1856-1861
Pearson, Gemma; Chai, Biaoxin; Vozheiko, Tracy et al. (2018) Clec16a, Nrdp1, and USP8 Form a Ubiquitin-Dependent Tripartite Complex That Regulates ?-Cell Mitophagy. Diabetes 67:265-277
Wang, Luhong; Burger, Laura L; Greenwald-Yarnell, Megan L et al. (2018) Glutamatergic Transmission to Hypothalamic Kisspeptin Neurons Is Differentially Regulated by Estradiol through Estrogen Receptor ? in Adult Female Mice. J Neurosci 38:1061-1072
Gregg, Brigid E; Botezatu, Nathalie; Brill, Joshua D et al. (2018) Gestational exposure to metformin programs improved glucose tolerance and insulin secretion in adult male mouse offspring. Sci Rep 8:5745
Semple, Erin; Hill, Jennifer W (2018) Sim1 Neurons Are Sufficient for MC4R-Mediated Sexual Function in Male Mice. Endocrinology 159:439-449
Ward, Kristen M; Yeoman, Larisa; McHugh, Cora et al. (2018) Atypical Antipsychotic Exposure May Not Differentiate Metabolic Phenotypes of Patients with Schizophrenia. Pharmacotherapy 38:638-650
Khan, Sabbir; Kowluru, Anjaneyulu (2018) CD36 mediates lipid accumulation in pancreatic beta cells under the duress of glucolipotoxic conditions: Novel roles of lysine deacetylases. Biochem Biophys Res Commun 495:2221-2226

Showing the most recent 10 out of 1823 publications