Abstract

The mission ofthe Center for Gastrointestinal Biology and Disease is to promote and enhance multidisciplinary digestive disease research. The center achieves this purpose through: ? Core laboratories that provide training, technical support, laboratory animals, reagents, and/or assays, ? A pilot/feasibility program that offers startup funds to junior investigators, or to established investigators who wish to pursue new directions in research, ? A scientific enrichment program.-- consisting of seminars, lectures by visiting scientists, workshops and research competitions for trainees ~ that improves the intellectual climate for gastrointestinal biological research, and promotes cooperation, collaboration and communication among involved personnel, and ? A professional development and training program that promotes the development of junior faculty and trainees.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK034987-28
Application #
8385559
Study Section
Special Emphasis Panel (ZDK1-GRB-8)
Project Start
Project End
Budget Start
2012-12-01
Budget End
2013-11-30
Support Year
28
Fiscal Year
2013
Total Cost
$566,158
Indirect Cost
$129,427

  Institution

Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Walker, Miriam Y; Pratap, Siddharth; Southerland, Janet H et al. (2018) Role of oral and gut microbiome in nitric oxide-mediated colon motility. Nitric Oxide 73:81-88
Smid, Marcela C; Ricks, Nitasha M; Panzer, Alexis et al. (2018) Maternal Gut Microbiome Biodiversity in Pregnancy. Am J Perinatol 35:24-30
Keith, Benjamin P; Barrow, Jasmine B; Toyonaga, Takahiko et al. (2018) Colonic epithelial miR-31 associates with the development of Crohn's phenotypes. JCI Insight 3:
Gracz, Adam D; Samsa, Leigh Ann; Fordham, Matthew J et al. (2018) Sox4 Promotes Atoh1-Independent Intestinal Secretory Differentiation Toward Tuft and Enteroendocrine Fates. Gastroenterology 155:1508-1523.e10
Mackie, Duncan I; Al Mutairi, Fuad; Davis, Reema B et al. (2018) hCALCRL mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia. J Exp Med 215:2339-2353
Evon, Donna M; Stewart, Paul W; Amador, Jipcy et al. (2018) A comprehensive assessment of patient reported symptom burden, medical comorbidities, and functional well being in patients initiating direct acting antiviral therapy for chronic hepatitis C: Results from a large US multi-center observational study. PLoS One 13:e0196908
Smith, Nicholas R; Swain, John R; Davies, Paige S et al. (2018) Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations. Cell Mol Gastroenterol Hepatol 6:79-96
Efird, William M; Fletcher, Alex G; Draeger, Reid W et al. (2018) Deferoxamine-Soaked Suture Improves Angiogenesis and Repair Potential After Acute Injury of the Chicken Achilles Tendon. Orthop J Sports Med 6:2325967118802792
Jacob, Noam; Jacobs, Jonathan P; Kumagai, Kotaro et al. (2018) Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome. Mucosal Immunol 11:1466-1476
Egberg, Matthew D; Mitchell, Paul D; Galanko, Joseph A et al. (2018) Effectiveness of oral iron supplementation in treatment of anemia associated with pediatric ulcerative colitis flare. Am J Hematol 93:E404-E406

Showing the most recent 10 out of 944 publications