The Hopkins Digestive Diseases Basic and Translational Research Core Center Administrative Core is the glue which forms the structure of this Center by carrying out communications among the Center and Research Base investigators and Core Directors, performing budget management, serving as a repertoire for the software used by Center investigators and organizing all Center activities. In this way the Research Base of 50 investigataors (38 full members 12 associate members) are allowed to efficiently interact with the components ofthe Core Center, including the a) Administrative Core;b) 4 Scientific Cores-3 basic science [1) Proteomics;2) Imaging;3) Mouse Physiology] and a Translational Research Enhancement Core;c) Pilot Project Program;d) Enrichement Program which has multiple components. The specific functions ofthe Administrative Core include: a) Provide administrative and financial management ofthe Core Center;b) Provide monthly financial statements to Core Directors;c) Monitor use and perform charge-back for each Core 6x year;d) Inform Research Base weekly of work-in-progress meeting topic, lectures of interest around Hopkins, NIH funding opportunities, GI histology findings on mouse models studied by Research Base, Visiting Professor Program, Yearly Scientic Symposium, Yearly Retreat;e) Arrange a yearly meeting of External Scientific Advisory Committee, every other month meeting of Internal Executive Committee and Focus Groups, 6x year Visiting Professor Program, and yearly working group meetings for each Core;f) Organize and run yearly Research Base one day retreat;g) Organize and run yearly 1-2 day long Research Symposium;h) Organize and publish yearly Core Center newsletter;i) Assist in preparation of yearly DDBTRCC Progress Report for NIH;j) Prepare notes from yearly External Scientific Advisory Committee meeting;k) Organize and administer Pilot Project Program;1) Organize and administer Mini-Sabbatical Program;m) Help Research Base comply with JHUSOM, NIH, other governmental guidelines relating to research;n) Develop web page for Imaging and Mouse Physiology Cores;o) Help manage DDBTRCC service contracts;p) Help negotiate Core Center purchasing of equipment, service contracts, software; q) Serve as a repository for licenses for software purchased for Research Base and Core use.

Public Health Relevance

The Administrafive core is the glue which forms the structure of this Core Center by communicating Core Center activities to the Research Base investigators. Core Directors, and Core Center leadership, performing budget management and serving as the site of storage of the Core Center software that is made available to the Research Base.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK089502-03
Application #
8461239
Study Section
Special Emphasis Panel (ZDK1-GRB-8)
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
3
Fiscal Year
2013
Total Cost
$398,243
Indirect Cost
$147,478
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Pierson, Hannah; Muchenditsi, Abigael; Kim, Byung-Eun et al. (2018) The Function of ATPase Copper Transporter ATP7B in Intestine. Gastroenterology 154:168-180.e5
Kim, Sangjune; Yun, Seung Pil; Lee, Saebom et al. (2018) GBA1 deficiency negatively affects physiological ?-synuclein tetramers and related multimers. Proc Natl Acad Sci U S A 115:798-803
Pilla, Scott J; Maruthur, Nisa M; Schweitzer, Michael A et al. (2018) The Role of Laboratory Testing in Differentiating Type 1 Diabetes from Type 2 Diabetes in Patients Undergoing Bariatric Surgery. Obes Surg 28:25-30
Rajkumar, Premraj; Cha, Boyoung; Yin, Jianyi et al. (2018) Identifying the localization and exploring a functional role for Gprc5c in the kidney. FASEB J 32:2046-2059
Pilla, Scott J; Yeh, Hsin-Chieh; Juraschek, Stephen P et al. (2018) Predictors of Insulin Initiation in Patients with Type 2 Diabetes: An Analysis of the Look AHEAD Randomized Trial. J Gen Intern Med 33:839-846
Yin, Jianyi; Tse, Chung-Ming; Avula, Leela Rani et al. (2018) Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers. Cell Mol Gastroenterol Hepatol 5:591-609
Kulkarni, Subhash; Ganz, Julia; Bayrer, James et al. (2018) Advances in Enteric Neurobiology: The ""Brain"" in the Gut in Health and Disease. J Neurosci 38:9346-9354
Bhattarai, Yogesh; Williams, Brianna B; Battaglioli, Eric J et al. (2018) Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion. Cell Host Microbe 23:775-785.e5
Avula, Leela Rani; Chen, Tiane; Kovbasnjuk, Olga et al. (2018) Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca2+, cGMP, and lysophosphatidic acid. Am J Physiol Gastrointest Liver Physiol 314:G81-G90
Moinova, Helen R; LaFramboise, Thomas; Lutterbaugh, James D et al. (2018) Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus. Sci Transl Med 10:

Showing the most recent 10 out of 232 publications