This module serves the computing needs of CVS Core users. The past five years have seen exciting developments in vision science and translational research in ophthalmology at Rochester. With those developments, the need for new software and new computing technologies has increased significantly. Perhaps most important among these changes have been the development of new multi-user research resources and the proliferation of several sets of common technologies to a number of different research communities within CVS. Multi-user resources within CVS include two virtual reality labs for the study of perceptual learning and multi-sensory integration in both normal subjects and patient populations, and a 52-processor computing cluster for data analysis and simulation of large-scale neural networks. Common technologies include a number of shared imaging devices (e.g., adaptive optics systems) used by both the retinal imaging and vision correction communities, common multi-electrode recording systems for electrophysiology, and common stimulus display systems used by both neurophysiology and behavioral labs. These shared resources will continue to require significant support from the computing module, which will make important contributions to projects that include: massively parallel simulations of neural networks, new virtual-reality software for multi-sensory integration experiments in both human and non-human primates, software development for multi-electrode recordings in non-human primates, and imaging the living human eye using adaptive optics. The computing module is staffed by three highly qualified full-time applications programmers who work closely with CVS investigators to implement novel software and hardware designs that enable new research projects.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY001319-40
Application #
8706873
Study Section
Special Emphasis Panel (ZEY1-VSN)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
40
Fiscal Year
2014
Total Cost
$215,858
Indirect Cost
$75,234
Name
University of Rochester
Department
Type
DUNS #
041294109
City
Rochester
State
NY
Country
United States
Zip Code
14627
Jeon, Kye-Im; Hindman, Holly B; Bubel, Tracy et al. (2018) Corneal myofibroblasts inhibit regenerating nerves during wound healing. Sci Rep 8:12945
Weiss, Menachem Y; Kuriyan, Ajay E (2018) Acute Monocular Vision Loss in a Young Adult. JAMA Ophthalmol 136:297-298
Chapman, Robert M; Gardner, Margaret N; Klorman, Rafael et al. (2018) Temporospatial components of brain ERPs as biomarkers for Alzheimer's disease. Alzheimers Dement (Amst) 10:604-614
Prentiss, Emily K; Schneider, Colleen L; Williams, Zoƫ R et al. (2018) Spontaneous in-flight accommodation of hand orientation to unseen grasp targets: A case of action blindsight. Cogn Neuropsychol 35:343-351
Bosen, Adam K; Fleming, Justin T; Allen, Paul D et al. (2018) Multiple time scales of the ventriloquism aftereffect. PLoS One 13:e0200930
Garcea, Frank E; Almeida, Jorge; Sims, Maxwell H et al. (2018) Domain-Specific Diaschisis: Lesions to Parietal Action Areas Modulate Neural Responses to Tools in the Ventral Stream. Cereb Cortex :
Song, Hongxin; Rossi, Ethan A; Stone, Edwin et al. (2018) Phenotypic diversity in autosomal-dominant cone-rod dystrophy elucidated by adaptive optics retinal imaging. Br J Ophthalmol 102:136-141
Schwarz, Christina; Sharma, Robin; Cheong, Soon Keen et al. (2018) Selective S Cone Damage and Retinal Remodeling Following Intense Ultrashort Pulse Laser Exposures in the Near-Infrared. Invest Ophthalmol Vis Sci 59:5973-5984
Cheong, Soon Keen; Strazzeri, Jennifer M; Williams, David R et al. (2018) All-optical recording and stimulation of retinal neurons in vivo in retinal degeneration mice. PLoS One 13:e0194947
Granger, Charles E; Yang, Qiang; Song, Hongxin et al. (2018) Human Retinal Pigment Epithelium: In Vivo Cell Morphometry, Multispectral Autofluorescence, and Relationship to Cone Mosaic. Invest Ophthalmol Vis Sci 59:5705-5716

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