We seek continued support for the Waisman Intellectual and Developmental Disabilities Research Center, a comprehensive interdisciplinary program on IDD spanning the biological, biobehavioral, and behavioral sciences. The Waisman IDDRC brings together 49 PIs from 25 academic departments from the UW-Madison Schools of Medicine and Public Health, Veterinary Medicine, Pharmacy, Agriculture and Life Sciences, Letters and Science, Education, and Human Ecology. This application requests support for an Administrative Core (Core A), providing scientific leadership, program and faculty development, facilitation of interdisciplinary collaboration, and biostatistical and bioinformatics expertise;ad four innovative scientific core services: Research Participation (Core B), providing services, resources, and training in the recruitment of human participants, clinical assessment, and behavioral methods development;Brain Imaging (Core C), providing access to state-of-the-art neuroimaging instrumentation (3T MRI, PET, and microPET scanners for human, non-human primate, and rodent scanning, and an EEG recording system), as well as expertise and tools for image acquisition and analysis;Rodent Models (Core D), providing resources, expertise, and technical services in the generation, cryopreservation, and maintenance of mutant or genetically engineered strains of mice, and advanced behavioral testing facilities for phenotypic characterization;and Cellular and Molecular Neuroscience (Core E), providing cellular and molecular neuroscience technology, training, and expertise, and supporting the generation of iPS cell lines from humans with IDD conditions. We propose to provide core support to 95 research projects headed by 49 PIs organized into three research groups: Molecular and Genetic Sciences, Communicative and Cognitive Sciences, and Social and Affective Sciences. Collectively, the core services and research groups of the Waisman Center IDDRC will stimulate new interdisciplinary IDD research and enhance existing IDD investigations, sharpening our focus on discovery, prevention, and treatment for IDD conditions and improvement of the quality of life of individuals with IDD and their families.
The mission of the Waisman IDDRC is to promote the highest level of IDD research by providing access to cutting-edge and efficient core services, seminars, and pre- and post-doctoral training via a comprehensive program designed to produce a transformative understanding of IDD pathology, development of new therapies, and training the next generation of basic and clinical IDD researchers.
|Lundwall, Rebecca A; Woodruff, Jason; Tolboe, Steven P (2018) RT Slowing to Valid Cues on a Reflexive Attention Task in Children and Young Adults. Front Psychol 9:1324|
|Hess, Christi L; Misurelli, Sara M; Litovsky, Ruth Y (2018) Spatial Release From Masking in 2-Year-Olds With Normal Hearing and With Bilateral Cochlear Implants. Trends Hear 22:2331216518775567|
|Laxman, D J; Greenberg, J S; DaWalt, L S et al. (2018) Medication use by adolescents and adults with fragile X syndrome. J Intellect Disabil Res 62:94-105|
|Li, James J; Lansford, Jennifer E (2018) A smartphone-based ecological momentary assessment of parental behavioral consistency: Associations with parental stress and child ADHD symptoms. Dev Psychol 54:1086-1098|
|Lundwall, Rebecca A; Sgro, Jordan F; Fanger, Julia (2018) Response time scores on a reflexive attention task predict a child's inattention score from a parent report. PLoS One 13:e0190724|
|Morrison, Ryann A; Martinez, Jonathan I; Hilton, Emily C et al. (2018) The influence of parents and schools on developmental trajectories of antisocial behaviors in Caucasian and African American youths. Dev Psychopathol :1-13|
|Patzlaff, Natalie E; Shen, Minjie; Zhao, Xinyu (2018) Regulation of Adult Neurogenesis by the Fragile X Family of RNA Binding Proteins. Brain Plast 3:205-223|
|Vijayan, Murali; Kumar, Subodh; Yin, Xiangling et al. (2018) Identification of novel circulatory microRNA signatures linked to patients with ischemic stroke. Hum Mol Genet 27:2318-2329|
|Plate, Rista C; Fulvio, Jacqueline M; Shutts, Kristin et al. (2018) Probability Learning: Changes in Behavior Across Time and Development. Child Dev 89:205-218|
|Hartley, Sigan L; Papp, Lauren M; Bolt, Daniel (2018) Spillover of Marital Interactions and Parenting Stress in Families of Children With Autism Spectrum Disorder. J Clin Child Adolesc Psychol 47:S88-S99|
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