Electrophysiology Core Overview This Core will allow investigators to determine the consequences of nervous system disease or injury at the level of neuronal activity and function. This will allow detailed analysis of nervous systems phenotypes by applying techniques not available in most labs. Nine Pis have utilized this Core under the current award leading to twelve papers and one new NIH grant.

National Institute of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Center Core Grants (P30)
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National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
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Ohio State University
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Meisen, Walter Hans; Dubin, Samuel; Sizemore, Steven T et al. (2015) Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies. Mol Cancer Ther 14:307-14
Bolyard, Chelsea; Yoo, Ji Young; Wang, Pin-Yi et al. (2014) Doxorubicin synergizes with 34.5ENVE to enhance antitumor efficacy against metastatic ovarian cancer. Clin Cancer Res 20:6479-94
Koemeter-Cox, Andrew I; Sherwood, Thomas W; Green, Jill A et al. (2014) Primary cilia enhance kisspeptin receptor signaling on gonadotropin-releasing hormone neurons. Proc Natl Acad Sci U S A 111:10335-40
Biswas, Sayantanee; Emond, Michelle R; Duy, Phan Q et al. (2014) Protocadherin-18b interacts with Nap1 to control motor axon growth and arborization in zebrafish. Mol Biol Cell 25:633-42
Tian, JinBin; Tep, Chhavy; Benedick, Alex et al. (2014) p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1. J Biol Chem 289:31458-72
Wojton, Jeffrey; Meisen, Walter Hans; Jacob, Naduparambil K et al. (2014) SapC-DOPS-induced lysosomal cell death synergizes with TMZ in glioblastoma. Oncotarget 5:9703-9
Janssen, Paul M L; Murray, Jason D; Schill, Kevin E et al. (2014) Prednisolone attenuates improvement of cardiac and skeletal contractile function and histopathology by lisinopril and spironolactone in the mdx mouse model of Duchenne muscular dystrophy. PLoS One 9:e88360
Nielson, Jessica L; Guandique, Cristian F; Liu, Aiwen W et al. (2014) Development of a database for translational spinal cord injury research. J Neurotrauma 31:1789-99
Thorne, Amy Haseley; Meisen, Walter H; Russell, Luke et al. (2014) Role of cysteine-rich 61 protein (CCN1) in macrophage-mediated oncolytic herpes simplex virus clearance. Mol Ther 22:1678-87
Sahinkaya, F Rezan; Milich, Lindsay M; McTigue, Dana M (2014) Changes in NG2 cells and oligodendrocytes in a new model of intraspinal hemorrhage. Exp Neurol 255:113-26

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