This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The long-term objective of this funded research is to treat type I Diabetes and to prevent its devastating complications using islet-cell xeno transplantation. Through the three funded program project grants we are actively exploring the use of porcine islets as an alternative to human islets for transplantation to reverse diabetes in humans. In this collaboration between the CMRR and the Diabetes Institute for Immunology and Transplantation (DIIT) at U of MN, our goal is to 1) assess the readiness and/or suitability of the transplantation site by measuring the vascularization with ultra high field (UHF) MRI and 2) assess the pre- and post-transplant viability of islets using magnetic resonance spectroscopy methods.

National Institute of Health (NIH)
National Center for Research Resources (NCRR)
Biotechnology Resource Grants (P41)
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Special Emphasis Panel (ZRG1-SBIB-S (40))
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University of Minnesota Twin Cities
Schools of Medicine
United States
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Lyzinski, Vince; Fishkind, Donniell E; Fiori, Marcelo et al. (2016) Graph Matching: Relax at Your Own Risk. IEEE Trans Pattern Anal Mach Intell 38:60-73
Kennedy, James T; Collins, Paul F; Luciana, Monica (2016) Higher Adolescent Body Mass Index Is Associated with Lower Regional Gray and White Matter Volumes and Lower Levels of Positive Emotionality. Front Neurosci 10:413
Sun, Yi; Brauckmann, Ole; Nixdorf, Donald R et al. (2016) Imaging human teeth by phosphorus magnetic resonance with nuclear Overhauser enhancement. Sci Rep 6:30756
Cusick, Sarah E; Georgieff, Michael K (2016) The Role of Nutrition in Brain Development: The Golden Opportunity of the ""First 1000 Days"". J Pediatr 175:16-21
Yang, X; Ding, H; Lu, J (2016) Feedback from visual cortical area 7 to areas 17 and 18 in cats: How neural web is woven during feedback. Neuroscience 312:190-200
Musgrove, Donald R; Hughes, John; Eberly, Lynn E (2016) Fast, fully Bayesian spatiotemporal inference for fMRI data. Biostatistics 17:291-303
Urošević, Snežana; Luciana, Monica; Jensen, Jonathan B et al. (2016) Age associations with neural processing of reward anticipation in adolescents with bipolar disorders. Neuroimage Clin 11:476-85
Goerke, Ute (2016) Spatial specificity in spatiotemporal encoding and Fourier imaging. Magn Reson Imaging 34:562-73
Andronesi, Ovidiu C; Loebel, Franziska; Bogner, Wolfgang et al. (2016) Treatment Response Assessment in IDH-Mutant Glioma Patients by Noninvasive 3D Functional Spectroscopic Mapping of 2-Hydroxyglutarate. Clin Cancer Res 22:1632-41
Bolan, Patrick J; Kim, Eunhee; Herman, Benjamin A et al. (2016) MR spectroscopy of breast cancer for assessing early treatment response: Results from the ACRIN 6657 MRS trial. J Magn Reson Imaging :

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