The Training Core will interact with all aspects of the Center by virtue of its goal, which is to facilitate the teaching of creative science thinking, especially by creating an atmosphere that nurtures students'creative insights (DeHaan, 2011). Creative insight stems from abstract thinking plus two types of mental operations: 1) associative (divergent) thinking involving thoughts that are defocused, intuitive and, importantly, receptive to a range of associations;and 2) analytical (convergent) thinking, i.e., the capacity to analyze, synthesize and focus (DeHaan, 2011). Furthermore, we are acutely aware of the need to train scientists who can work across traditional disciplinary boundaries. Thus, we are striving for an integrated model for science education (Lorsch and Nichols, 2011) that provides interdisciplinary training that enables trainees to speak the many scientific languages spoken across the range of the research undertaken by the SRP Center investigative team. Our hypothesis is that cross-training of students participating in the MSU P42 Center Grant in disciplines not traditionally linked with the university structure will be achieved through a multifaceted training approach involving laboratory based research combined with formal and informal instruction.
The Specific Aims are: SAI) Provide interdisciplinary training to predoctoral and postdoctoral students through research collaborations across biomedical and non-biomedical research projects and cores within the Michigan State University Superfund Research Program (MSU SRP) Center;SA2) Provide interdisciplinary training to predoctoral and postdoctoral students through a monthly journal club;and SA3) Provide interdisciplinary training to predoctoral and postdoctoral students through formal instruction (e.g.. Computational Biology and Dose Response courses, Distinguished Scholars in Toxicology Lecture Series as well as other seminars on the MSU campus, travel to provide special educational opportunities and elective courses designed to facilitate designed to facilitate movement towards "Convergence" the third revolution in the biological sciences, i.e., convergence ofthe life sciences, engineering and the physical sciences Sharp et al., 2011). The implementation of these specific aims will, in a synergistic fashion, facilitate the training of graduate students and postdoctoral fellows who will be afforded a forward thinking interdisciplinary focus and, therefore, be prepared to tackle current and future environmentally-related human health issues.
The Training Core has developed an innovative combination of activities involving fostering research that crosses/bridges biomedical, environmental, and engineering research, an interdisciplinary Journal Club and interdisciplinary training through formal instruction. These is designed to facilitate integration of the SRP investigative team's research efforts through a coordinated multifaceted training program which emphasizes cross disciplinary approaches to the research efforts at hand.
|Cole, James R; Tiedje, James M (2014) History and impact of RDP: a legacy from Carl Woese to microbiology. RNA Biol 11:239-43|
|Cole, James R; Wang, Qiong; Fish, Jordan A et al. (2014) Ribosomal Database Project: data and tools for high throughput rRNA analysis. Nucleic Acids Res 42:D633-42|
|Rhodes, Albert N; Fulthorpe, Roberta R; Tiedje, James M (2013) Probing the functional diversity of global pristine soil communities with 3-chlorobenzoate reveals that communities of generalists dominate catabolic transformation. Appl Environ Microbiol 79:6932-40|
|Forgacs, Agnes L; Dere, Edward; Angrish, Michelle M et al. (2013) Comparative analysis of temporal and dose-dependent TCDD-elicited gene expression in human, mouse, and rat primary hepatocytes. Toxicol Sci 133:54-66|
|Kopec, Anna K; Boverhof, Darrell R; Nault, Rance et al. (2013) Toxicogenomic evaluation of long-term hepatic effects of TCDD in immature, ovariectomized C57BL/6 mice. Toxicol Sci 135:465-75|
|Zhang, Qiang; Kline, Douglas E; Bhattacharya, Sudin et al. (2013) All-or-none suppression of B cell terminal differentiation by environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol 268:17-26|
|Fullerton, Aaron M; Roth, Robert A; Ganey, Patricia E (2013) 2,3,7,8-TCDD enhances the sensitivity of mice to concanavalin A immune-mediated liver injury. Toxicol Appl Pharmacol 266:317-27|
|Angrish, Michelle Manente; Dominici, Claudia Yvette; Zacharewski, Timothy Richard (2013) TCDD-elicited effects on liver, serum, and adipose lipid composition in C57BL/6 mice. Toxicol Sci 131:108-15|
|Zhang, Qiang; Bhattacharya, Sudin; Andersen, Melvin E (2013) Ultrasensitive response motifs: basic amplifiers in molecular signalling networks. Open Biol 3:130031|
|Nault, Rance; Forgacs, Agnes L; Dere, Edward et al. (2013) Comparisons of differential gene expression elicited by TCDD, PCB126, *NF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver. Toxicol Lett 223:52-9|
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