This application proposes to develop three key components in person-centered longitudinal statistical models: (a) a comprehensive simulation study designed to understand the nuanced performance of a wide range of models used to derive group based trajectories, (b) a cross-validation procedure designed to bolster the confidence (in terms of replication and consistency) of these models when employed in controlled, clinical trials and effectiveness trials, and (c) to promote dissemination of these advanced techniques by developing a user- friendly, freely available software with a graphical-user interface.

Public Health Relevance

This application, through comprehensive simulation and benchmarking, develops a foundation for assessing the quality of person-centered longitudinal statistical methods. These methodological developments will provide an advancement in terms of real world data analysis by extending the potential models for identifying relevant mediators, moderators, and predictors in controlled, clinical trials and effectiveness trials.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
1R01AA023248-01
Application #
8750040
Study Section
Risk, Prevention and Intervention for Addictions Study Section (RPIA)
Program Officer
Zha, Wenxing
Project Start
2014-09-15
Project End
2017-06-30
Budget Start
2014-09-15
Budget End
2015-06-30
Support Year
1
Fiscal Year
2014
Total Cost
$381,846
Indirect Cost
$122,292
Name
University of Missouri-Columbia
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
153890272
City
Columbia
State
MO
Country
United States
Zip Code
65211