The research described in this competing renewal proposal seeks through five aims to maintain and enhance the Americans'Changing Lives (ACL) study, which was started in 1986, and is the oldest on-going nationally- representative prospective study of a broad range of socioeconomic and psychosocial determinants of health, and of how health and health disparities play out over the full life course. It is a unique research project and major public use data set for analyzing and understanding social disparities in the way health changes with age, especially the postponement or compression of mortality, morbidity, functional limitations, and disability over the entire adult life course. The ACL study focuses on and contributes to the two overarching goals of the U.S. Public Health Service's Healthy People 2010 strategic plan: 1) increasing healthy active life expectancy and 2) reducing social disparities in health. The five specific aims of this proposal are: 1) to extend the longitudinal follow-up of surviving members of the 1986 ACL sample by conducting a fifth wave of data collection and continuing annual mortality ascertainment using the National Death Index, death certificate verification, and other mortality tracking processes through at least 2013;2) to develop a methodological/biostatistical core for ACL which will a) provide expertise to the project for increasingly complex analyses of the determinants of long term changes and trajectories in health, and b) develop and apply innovative statistical/methodological research to improve longitudinal analysis and adjust for selection and attrition in analyses, thus, improving our and others'ability to utilize ACL and similar longitudinal data;3) to understand mechanisms underlying social disparities in morbidity and mortality and the compression thereof;4) to add new measures regarding medical care, disability and impairment to ACL Wave 5 so as to expand the health status outcomes under study and investigate the role of selected biomedical interventions in maintaining, enhancing or alleviating social disparities in the way different health outcomes change with age;and 5) to capitalize on existing measures of work conditions and transitions and add new ones to ACL5 in order to investigate changing patterns and sequencing of paid work, unpaid productive activities, and "retirement", in the context of current crises of the American and world economies.

Public Health Relevance

This project extends the Americans'Changing Lives (ACL) - a national longitudinal study of social determinants of and disparities in health and the way health changes with age. The proposed project would re-interview survivors a fifth time and extend mortality follow-up through at least 2013. The study focuses on and contributes to the two overarching goals of the U.S. Public Health Service: increasing healthy active life expectancy and reducing social disparities in health.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Research Project (R01)
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Study Section
Special Emphasis Panel (ZRG1-PSE-B (04))
Program Officer
Patmios, Georgeanne E
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University of Michigan Ann Arbor
Biostatistics & Other Math Sci
Organized Research Units
Ann Arbor
United States
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Burgard, Sarah A; Elliott, Michael R; Zivin, Kara et al. (2013) Working conditions and depressive symptoms: a prospective study of US adults. J Occup Environ Med 55:1007-14
Infurna, Frank J; Gerstorf, Denis; Zarit, Steven H (2011) Examining dynamic links between perceived control and health: longitudinal evidence for differential effects in midlife and old age. Dev Psychol 47:9-18
Clarke, Philippa; Marshall, Victor; House, James et al. (2011) The Social Structuring of Mental Health over the Adult Life Course: Advancing Theory in the Sociology of Aging. Soc Forces 89:1287-1313
Lantz, Paula M; Golberstein, Ezra; House, James S et al. (2010) Socioeconomic and behavioral risk factors for mortality in a national 19-year prospective study of U.S. adults. Soc Sci Med 70:1558-66
Clarke, Philippa; Ailshire, Jennifer A; Lantz, Paula (2009) Urban built environments and trajectories of mobility disability: findings from a national sample of community-dwelling American adults (1986-2001). Soc Sci Med 69:964-70
Mohai, Paul; Lantz, Paula M; Morenoff, Jeffrey et al. (2009) Racial and socioeconomic disparities in residential proximity to polluting industrial facilities: evidence from the Americans'Changing Lives Study. Am J Public Health 99 Suppl 3:S649-56
Burgard, Sarah A; Brand, Jennie E; House, James S (2009) Perceived job insecurity and worker health in the United States. Soc Sci Med 69:777-85
Burgard, Sarah A; Brand, Jennie E; House, James S (2007) Toward a better estimation of the effect of job loss on health. J Health Soc Behav 48:369-84
House, James S; Lantz, Paula M; Herd, Pamela (2005) Continuity and change in the social stratification of aging and health over the life course: evidence from a nationally representative longitudinal study from 1986 to 2001/2002 (Americans' Changing Lives Study). J Gerontol B Psychol Sci Soc Sci 60 Spec No 2:15-26
Lantz, Paula M; House, James S; Mero, Richard P et al. (2005) Stress, life events, and socioeconomic disparities in health: results from the Americans' Changing Lives Study. J Health Soc Behav 46:274-88

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