Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI023847-09
Application #
2062357
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1988-04-01
Project End
1997-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Surgery
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Ji, Haofeng; Shen, Xiu-Da; Gao, Feng et al. (2011) Alloreactive CD8 T-cell primed/memory responses and accelerated graft rejection in B-cell-deficient sensitized mice. Transplantation 91:1075-81
Shen, Xiu-Da; Ke, Bibo; Uchida, Yoichiro et al. (2011) Native macrophages genetically modified to express heme oxygenase 1 protect rat liver transplants from ischemia/reperfusion injury. Liver Transpl 17:201-10
Uchida, Yoichiro; Freitas, Maria Cecilia S; Zhao, Danyun et al. (2010) The protective function of neutrophil elastase inhibitor in liver ischemia/reperfusion injury. Transplantation 89:1050-6
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Uchida, Yoichiro; Ke, Bibo; Freitas, Maria Cecilia S et al. (2010) T-cell immunoglobulin mucin-3 determines severity of liver ischemia/reperfusion injury in mice in a TLR4-dependent manner. Gastroenterology 139:2195-206
Ji, Haofeng; Shen, Xiuda; Gao, Feng et al. (2010) Programmed death-1/B7-H1 negative costimulation protects mouse liver against ischemia and reperfusion injury. Hepatology 52:1380-9
Ke, Bibo; Shen, Xiu-Da; Gao, Feng et al. (2010) Adoptive transfer of ex vivo HO-1 modified bone marrow-derived macrophages prevents liver ischemia and reperfusion injury. Mol Ther 18:1019-25
Uchida, Yoichiro; Ke, Bibo; Freitas, Maria Cecilia S et al. (2010) The emerging role of T cell immunoglobulin mucin-1 in the mechanism of liver ischemia and reperfusion injury in the mouse. Hepatology 51:1363-72
Liu, Dahai; Shen, Xiu-Da; Zhai, Yuan et al. (2009) Intragraft selection of the T cell receptor repertoire by class I MHC sequences in tolerant recipients. PLoS One 4:e6076
Uchida, Yoichiro; Freitas, Maria Cecilia S; Zhao, Danyun et al. (2009) The inhibition of neutrophil elastase ameliorates mouse liver damage due to ischemia and reperfusion. Liver Transpl 15:939-47

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