Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI027044-08
Application #
2063687
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1993-12-01
Project End
1998-05-31
Budget Start
1995-12-01
Budget End
1998-05-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
New York State Department of Health
Department
Type
DUNS #
002436061
City
Menands
State
NY
Country
United States
Zip Code
12204
Coleman, James L; Toledo, Alvaro; Benach, Jorge L (2018) HtrA of Borrelia burgdorferi Leads to Decreased Swarm Motility and Decreased Production of Pyruvate. MBio 9:
Toledo, Alvaro; Huang, Zhen; Benach, Jorge L et al. (2018) Analysis of Lipids and Lipid Rafts in Borrelia. Methods Mol Biol 1690:69-82
Toledo, Alvaro; Huang, Zhen; Coleman, James L et al. (2018) Lipid rafts can form in the inner and outer membranes of Borrelia burgdorferi and have different properties and associated proteins. Mol Microbiol 108:63-76
Huang, Zhen; Toledo, Alvaro M; Benach, Jorge L et al. (2016) Ordered Membrane Domain-Forming Properties of the Lipids of Borrelia burgdorferi. Biophys J 111:2666-2675
Monzón, Javier D; Atkinson, Elizabeth G; Henn, Brenna M et al. (2016) Population and Evolutionary Genomics of Amblyomma americanum, an Expanding Arthropod Disease Vector. Genome Biol Evol 8:1351-60
Coleman, James L; Toledo, Alvaro; Benach, Jorge L (2016) Borrelia burgdorferi?HtrA: evidence for twofold proteolysis of outer membrane protein p66. Mol Microbiol 99:135-50
Toledo, Alvaro; Pérez, Alberto; Coleman, James L et al. (2015) The lipid raft proteome of Borrelia burgdorferi. Proteomics 15:3662-75
Katona, Laura I (2015) The Fur homologue BosR requires Arg39 to activate rpoS transcription in Borrelia burgdorferi and thereby direct spirochaete infection in mice. Microbiology 161:2243-55
Toledo, Alvaro; Monzón, Javier D; Coleman, James L et al. (2015) Hypercholesterolemia and ApoE deficiency result in severe infection with Lyme disease and relapsing-fever Borrelia. Proc Natl Acad Sci U S A 112:5491-6
Toledo, Alvaro; Benach, Jorge L (2015) Hijacking and Use of Host Lipids by Intracellular Pathogens. Microbiol Spectr 3:

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