Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI033713-04
Application #
2068785
Study Section
Special Emphasis Panel (ZRG5-BM-2 (04))
Project Start
1993-01-01
Project End
2000-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Rochester
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Lamb, Janet R; Patel, Hetal; Montminy, Timothy et al. (2003) Functional domains of the RhlR transcriptional regulator of Pseudomonas aeruginosa. J Bacteriol 185:7129-39
Smith, Roger S; Harris, Sarah G; Phipps, Richard et al. (2002) The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)homoserine lactone contributes to virulence and induces inflammation in vivo. J Bacteriol 184:1132-9
Smith, Roger S; Kelly, Rodney; Iglewski, Barbara H et al. (2002) The Pseudomonas autoinducer N-(3-oxododecanoyl) homoserine lactone induces cyclooxygenase-2 and prostaglandin E2 production in human lung fibroblasts: implications for inflammation. J Immunol 169:2636-42
De Kievit, T R; Gillis, R; Marx, S et al. (2001) Quorum-sensing genes in Pseudomonas aeruginosa biofilms: their role and expression patterns. Appl Environ Microbiol 67:1865-73
De Kievit, T R; Parkins, M D; Gillis, R J et al. (2001) Multidrug efflux pumps: expression patterns and contribution to antibiotic resistance in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother 45:1761-70
McKnight, S L; Iglewski, B H; Pesci, E C (2000) The Pseudomonas quinolone signal regulates rhl quorum sensing in Pseudomonas aeruginosa. J Bacteriol 182:2702-8
Hassett, D J; Ma, J F; Elkins, J G et al. (1999) Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide. Mol Microbiol 34:1082-93
Pesci, E C; Milbank, J B; Pearson, J P et al. (1999) Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 96:11229-34
Glessner, A; Smith, R S; Iglewski, B H et al. (1999) Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of twitching motility. J Bacteriol 181:1623-9
Kline, T; Bowman, J; Iglewski, B H et al. (1999) Novel synthetic analogs of the Pseudomonas autoinducer. Bioorg Med Chem Lett 9:3447-52

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