Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI084119-04S1
Application #
8733248
Study Section
Program Officer
Malaspina, Angela
Project Start
2014-01-29
Project End
2016-01-28
Budget Start
2014-01-29
Budget End
2016-01-28
Support Year
4
Fiscal Year
2014
Total Cost
Indirect Cost
Name
New York University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Pan, Ruimin; Gorny, Miroslaw K; Zolla-Pazner, Susan et al. (2015) The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel. J Virol 89:8003-10
Shmelkov, Evgeny; Grigoryan, Arsen; Krachmarov, Chavdar et al. (2014) Sequence-conserved and antibody-accessible sites in the V1V2 domain of HIV-1 gp120 envelope protein. AIDS Res Hum Retroviruses 30:927-31
Shmelkov, Evgeny; Nadas, Arthur; Cardozo, Timothy (2014) Could vaccination with AIDSVAX immunogens have resulted in antibody-dependent enhancement of HIV infection in human subjects? Hum Vaccin Immunother 10:3013-6
Cardozo, Timothy; Wang, Shixia; Jiang, Xunqing et al. (2014) Vaccine focusing to cross-subtype HIV-1 gp120 variable loop epitopes. Vaccine 32:4916-24
Spurrier, Brett; Sampson, Jared; Gorny, Miroslaw K et al. (2014) Functional implications of the binding mode of a human conformation-dependent V2 monoclonal antibody against HIV. J Virol 88:4100-12
Zolla-Pazner, Susan; deCamp, Allan C; Cardozo, Timothy et al. (2013) Analysis of V2 antibody responses induced in vaccinees in the ALVAC/AIDSVAX HIV-1 vaccine efficacy trial. PLoS One 8:e53629
Gorny, Miroslaw K; Pan, Ruimin; Williams, Constance et al. (2012) Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals. Virology 427:198-207
Karasavvas, Nicos; Billings, Erik; Rao, Mangala et al. (2012) The Thai Phase III HIV Type 1 Vaccine trial (RV144) regimen induces antibodies that target conserved regions within the V2 loop of gp120. AIDS Res Hum Retroviruses 28:1444-57
Agarwal, Alpna; Hioe, Catarina E; Swetnam, James et al. (2011) Quantitative assessment of masking of neutralization epitopes in HIV-1. Vaccine 29:6736-41
Spurrier, Brett; Sampson, Jared M; Totrov, Maxim et al. (2011) Structural analysis of human and macaque mAbs 2909 and 2.5B: implications for the configuration of the quaternary neutralizing epitope of HIV-1 gp120. Structure 19:691-9

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