Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR030988-22
Application #
6697311
Study Section
Special Emphasis Panel (ZRG1-SMB (01))
Program Officer
Lymn, Richard W
Project Start
1982-05-01
Project End
2008-01-31
Budget Start
2004-02-01
Budget End
2005-01-31
Support Year
22
Fiscal Year
2004
Total Cost
$258,869
Indirect Cost
Name
University of California Los Angeles
Department
Physiology
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Siththanandan, V B; Tobacman, L S; Van Gorder, N et al. (2009) Mechanical and kinetic effects of shortened tropomyosin reconstituted into myofibrils. Pflugers Arch 458:761-76
Sumandea, Marius P; Vahebi, Susan; Sumandea, C Amelia et al. (2009) Impact of cardiac troponin T N-terminal deletion and phosphorylation on myofilament function. Biochemistry 48:7722-31
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Karibe, A; Tobacman, L S; Strand, J et al. (2001) Hypertrophic cardiomyopathy caused by a novel alpha-tropomyosin mutation (V95A) is associated with mild cardiac phenotype, abnormal calcium binding to troponin, abnormal myosin cycling, and poor prognosis. Circulation 103:65-71
Strand, J; Nili, M; Homsher, E et al. (2001) Modulation of myosin function by isoform-specific properties of Saccharomyces cerevisiae and muscle tropomyosins. J Biol Chem 276:34832-9
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