Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM053525-02
Application #
2192899
Study Section
Molecular Biology Study Section (MBY)
Project Start
1995-09-30
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Duke University
Department
Surgery
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705

  Publications

Watanabe, T; Sullenger, B A (2000) Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts. Proc Natl Acad Sci U S A 97:8490-4
Zarrinkar, P P; Sullenger, B A (1999) Optimizing the substrate specificity of a group I intron ribozyme. Biochemistry 38:3426-32
Long, M B; Sullenger, B A (1999) Evaluating group I intron catalytic efficiency in mammalian cells. Mol Cell Biol 19:6479-87
Zarrinkar, P P; Sullenger, B A (1998) Probing the interplay between the two steps of group I intron splicing: competition of exogenous guanosine with omega G. Biochemistry 37:18056-63
Jones, J T; Sullenger, B A (1997) Evaluating and enhancing ribozyme reaction efficiency in mammalian cells. Nat Biotechnol 15:902-5
Jones, J T; Lee, S W; Sullenger, B A (1996) Tagging ribozyme reaction sites to follow trans-splicing in mammalian cells. Nat Med 2:643-8