This proposal is divided into three sections, each with a separate, specific objective. The first section of the proposal is entitled """"""""The Surgical Treatment of Supraventricular Tachyarrhythmias"""""""" and is designed to expand and define the role of surgery in the treatment of certain types of supraventricular tachyarrhythmias, including ectopic (automatic) left atrial tachycardia, atrial flutter/fibrillation associated with mitral valve disease, AV node reentry tachycardia, and postoperative atrial flutter/fibrillation following elective cardioplegic arrest. The second section of the proposal is entitled """"""""The Surgical Treatment of Ventricular Tachyarrhythmias"""""""" and is designed to determine the effectiveness and side-effects of new direct surgical techniques for the treatment of refractory ischemic ventricular tachycardia and to develop safe and effective surgical approaches to the treatment of ventricular tachyarrhythmias that are not associated with ischemic heart disease, particularly those originating in the right ventricle. The third section of the proposal is entitled """"""""The Development of an Intraoperative and Postoperative Electrophysiologic Monitoring System"""""""" and is designed to establish a method by which myocardia integrity can be monitored on a continuous, real-time basis during and after cardiac surgical procedures.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL032257-03
Application #
3343588
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1983-08-08
Project End
1986-07-31
Budget Start
1985-08-01
Budget End
1986-07-31
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Khiabani, Ali J; Adademir, Taylan; Schuessler, Richard B et al. (2018) Management of Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Grafting: Review of the Literature. Innovations (Phila) 13:383-390
Musharbash, Farah N; Schill, Matthew R; Hansalia, Vivek H et al. (2018) Minimally Invasive Versus Full-Sternotomy Septal Myectomy for Hypertrophic Cardiomyopathy. Innovations (Phila) 13:261-266
Musharbash, Farah N; Schill, Matthew R; Sinn, Laurie A et al. (2018) Performance of the Cox-maze IV procedure is associated with improved long-term survival in patients with atrial fibrillation undergoing cardiac surgery. J Thorac Cardiovasc Surg 155:159-170
Ruaengsri, Chawannuch; Schill, Matthew R; Khiabani, Ali J et al. (2018) The Cox-maze IV procedure in its second decade: still the gold standard? Eur J Cardiothorac Surg 53:i19-i25
Schill, Matthew R; Musharbash, Farah N; Hansalia, Vivek et al. (2017) Late results of the Cox-maze IV procedure in patients undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg 153:1087-1094
Musharbash, Farah N; Schill, Matthew R; Henn, Matthew C et al. (2017) Minimally Invasive Septal Myectomy for Hypertrophic Obstructive Cardiomyopathy. Innovations (Phila) 12:489-492
Schill, Matthew R; Sinn, Laurie A; Greenberg, Jason W et al. (2017) A Minimally Invasive Stand-alone Cox-Maze Procedure Is as Effective as Median Sternotomy Approach. Innovations (Phila) 12:186-191
Schill, Matthew R; Melby, Spencer J; Speltz, Molly et al. (2017) Evaluation of a Novel Cryoprobe for Atrial Ablation in a Chronic Ovine Model. Ann Thorac Surg 104:1069-1073
Badhwar, Vinay; Rankin, J Scott; Damiano Jr, Ralph J et al. (2017) The Society of Thoracic Surgeons 2017 Clinical Practice Guidelines for the Surgical Treatment of Atrial Fibrillation. Ann Thorac Surg 103:329-341
Ishii, Yosuke; Schuessler, Richard B; Gaynor, Sydney L et al. (2017) Postoperative atrial fibrillation: The role of the inflammatory response. J Thorac Cardiovasc Surg 153:1357-1365

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