Involvement with the criminal justice system, substance use, and infection with HIV and hepatitis C virus (HCV) are syndemic in the United States. Persons involved with the criminal justice (CJ) system are more likely to use substances, have comorbid mental health conditions, limited access to health care and health insurance, and have higher rates of HIV and HCV infection than the general population. Furthermore, incarcerated populations are also more likely to be racial and ethnic minorities and be economically and educationally disadvantaged. Research exploring these phenomena is insufficient. To address these disparities and increase the number and capacity of clinical scientists working with CJ populations, we established The Lifespan/Brown Criminal Justice Research Program on Substance Use and HIV (referred to as the CJRT) in 2014. Following a successful initial funding cycle during which we enrolled 22 scholars, we seek renewal funding to sustain this important and innovative training program. The CJRT program recruits an annual cohort of 4-5 scholars consisting of exceptionally qualified pre-doctoral, post-doctoral, and junior faculty researchers from the United States. The program is led by an experienced team of investigators from Brown University who collectively have several decades of experience conducting research among CJ-involved populations within local, national and international settings; and who have extensive mentoring experience with early career investigators. The mission of the CJRT program is to prepare scholars for independent NIH-funded clinical research careers focused on improving health outcomes related to substance use, HIV and HCV infection, and related co-morbidities among persons who are involved with the CJ system. The CJRT educational program is comprised of didactic education, mentored research, and experiential learning. CJRT scholars are enrolled for a two-year period and pursue research at their home institution under the guidance of both local and CJRT mentors. The program has the following three aims: 1) provide scholars with a solid foundation for clinical research related to CJ populations that includes skills in research methodology, scientific writing, grant writing, dissemination, and the ethics and practice of conducting research among vulnerable populations; 2) provide professional mentorship and guidance to support the career advancement of junior investigators; and 3) provide a mentored research experience including funds for pilot projects that provides a supportive pathway to research independence. For the next funding period, the CJRT program will highlight two new areas of training: 1) research related to the opioid crisis and overdose epidemic, given the public health urgency of this epidemic and direct relevance to CJ-populations; and 2) implementation science, given the need to effectively roll-out and expand access to evidence-based interventions for CJ-involved populations. Scientific guidance and program evaluation are strengthened by an Executive Committee and an External Advisory Committee.

Public Health Relevance

Involvement with the criminal justice system, substance use, and infection with HIV and hepatitis C virus are syndemic in the United States. Despite this public health crisis, there is a relative dearth of clinical research aimed at improving treatment outcomes among CJ populations. To address this gap and increase the number and capacity of clinical scientists working with criminal justice-involved populations, we have established this clinical research training program based at the Providence-Boston Center for AIDS Research (CFAR) and in collaboration with the Brown University and Boston University Schools of Public Health.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Education Projects (R25)
Project #
Application #
Study Section
Special Emphasis Panel (ZDA1)
Program Officer
Mulford, Carrie Fried
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Miriam Hospital
United States
Zip Code
Zielinski, Melissa J; Veilleux, Jennifer C (2018) The Perceived Invalidation of Emotion Scale (PIES): Development and psychometric properties of a novel measure of current emotion invalidation. Psychol Assess 30:1454-1467
Brinkley-Rubinstein, Lauren; McKenzie, Michelle; Macmadu, Alexandria et al. (2018) A randomized, open label trial of methadone continuation versus forced withdrawal in a combined US prison and jail: Findings at 12 months post-release. Drug Alcohol Depend 184:57-63
Nowotny, Kathryn M; Frankeberger, Jessica; Rodriguez, Victoria E et al. (2018) Behavioral, Psychological, Gender, and Health Service Correlates to Herpes Simplex Virus Type 2 Infection among Young Adult Mexican-American Women Living in a Disadvantaged Community. Behav Med :1-10
Barocas, Joshua A; Tasillo, Abriana; Eftekhari Yazdi, Golnaz et al. (2018) Population-level Outcomes and Cost-Effectiveness of Expanding the Recommendation for Age-based Hepatitis C Testing in the United States. Clin Infect Dis 67:549-556
Barocas, Joshua A; White, Laura F; Wang, Jianing et al. (2018) Estimated Prevalence of Opioid Use Disorder in Massachusetts, 2011-2015: A Capture-Recapture Analysis. Am J Public Health 108:1675-1681
Dauria, Emily; Tolou-Shams, Marina; Skipalska, Halyna et al. (2018) Outcomes of the ""STEPS"" HIV prevention training program for young males in the penitentiary institution, Ukraine. Int J Prison Health 14:101-108
Brinkley-Rubinstein, Lauren; Macmadu, Alexandria; Marshall, Brandon D L et al. (2018) Risk of fentanyl-involved overdose among those with past year incarceration: Findings from a recent outbreak in 2014 and 2015. Drug Alcohol Depend 185:189-191
Hodges, Jacqueline; Reyes, Jessica; Campbell, Joyce et al. (2018) Successful Implementation of a Shared Medical Appointment Model for Hepatitis C Treatment at a Community Health Center. J Community Health :
Dong, Kimberly R; Must, Aviva; Tang, Alice M et al. (2018) Food Insecurity, Morbidities, and Substance Use in Adults on Probation in Rhode Island. J Urban Health 95:564-575
Zielinski, Melissa J; Hill, Morgan A; Veilleux, Jennifer C (2018) Is the first cut really the deepest? Frequency and recency of nonsuicidal self-injury in relation to psychopathology and dysregulation. Psychiatry Res 259:392-397

Showing the most recent 10 out of 24 publications