Patients'knowledge concerning their chronic illness has long been considered """"""""necessary but not sufficient"""""""" to produce changes in risk-related behaviors. """"""""Necessary"""""""" implies that patient knowledge is, therefore, a moderator of the effectiveness of behavioral interventions. However, researchers have tended to ignore patient education as a critical component of behavioral (or, for that matter, pharmacological) interventions. We propose to combine a behavioral intervention that we and others have found to be moderately effective in increasing blood pressure (BP) control in hypertensive patients - using a home BP monitor (HBPM) to obtain feedback regarding their BP control, and providing feedback to the health provider - with a systematic patient education component. We propose an intervention strategy that is meant to be usable as an adjunct to the HBPM and other interventions;one that will increase patients'knowledge, and, we hypothesize, will therefore increase the effectiveness of the """"""""parent"""""""" intervention (HBPM, in this case). Our proposal is for a randomized controlled trial (RCT), using a 2X2 factorial design in which we will test the effect of (1) a patient education intervention and (2) HBPM, on ambulatory BP in poorly-controlled hypertensive patients at 3 and 6 months. The education intervention is based on a technique called """"""""Self-Paced Programmed Instruction"""""""" (SPPI), a method that has been remarkably effective at increasing knowledge concerning complex topics. Using a computer, a paragraph of content material is presented, followed by probe questions. When patients provide a correct response, they are immediately reinforced by positive feedback;an incorrect response loops the program to re-present the materials, this time with hints;and the subjects then re-attempt the probe questions. The loop continues until a correct answer is recorded. In this manner, every subject achieves mastery over the requisite material. We posit that medication adherence (assessed objectively) will partially mediate the ambulatory BP outcomes;and that Self-Efficacy for the self- management of HTN will mediate medication adherence;we predict that self-efficacy will be enhanced by the mastery of the HTN-related materials, and by the reduction of ambiguity, which will lead to greater confidence in the patient's decision-making processes. We predict that the SPPI - HBPM condition will have the greatest effect on ambulatory BP, compared to the other three groups.

Public Health Relevance

Hypertension remains a hugely costly problem in the United States in terms of morbidity and economic burden. Many patients cannot or will not take medications;the application proposes a non-pharmacological intervention that will help hypertensive patients adhere to their prescribed medication regimens, and to control their blood pressure.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL089402-02
Application #
7933829
Study Section
Behavioral Medicine, Interventions and Outcomes Study Section (BMIO)
Program Officer
Czajkowski, Susan
Project Start
2009-09-30
Project End
2012-07-31
Budget Start
2010-08-01
Budget End
2012-07-31
Support Year
2
Fiscal Year
2010
Total Cost
$752,162
Indirect Cost
Name
Pennsylvania State University
Department
Psychology
Type
Schools of Allied Health Profes
DUNS #
003403953
City
University Park
State
PA
Country
United States
Zip Code
16802
Williams, Olajide; DeSorbo, Alexandra; Noble, James et al. (2012) Child-Mediated Stroke Communication: findings from Hip Hop Stroke. Stroke 43:163-9
Williams, Olajide; DeSorbo, Alexandra; Noble, James et al. (2012) Long-term learning of stroke knowledge among children in a high-risk community. Neurology 79:802-6