HIV/AIDS is a major contributor to morbidity and mortality in Uganda. Despite aggressive advances in HIV prevention efforts, recent data suggest that HIV prevalence is increasing generally, and HIV knowledge, a direct contributor to behavior, is on the decline among young people specifically as compared to a decade ago. The Internet is a promising mode of intervention delivery in resource poor-settings because the costs associated with scaling up are minimal;dissemination online is the same if one person or 100,000 people use the program. Just as important, it provides access to important health information in a stigma-free, anonymous atmosphere. Our recent data indicate that 45% of adolescents in Mbarara, Uganda have used the Internet, 78% of whom went online at least once in the previous week. Eighty-one percent of respondents in the same survey indicated they would go to an HIV prevention web site if it existed. Based upon these data, we propose to develop a culturally appropriate, Internet-based HIV prevention program designed specifically for Ugandan adolescents between the ages of 12 and 18 years.
Our specific aims are as follows:
Specific Aim 1 : Design a 6-hour, Internet-based HIV prevention program for adolescents. Content will be culturally tailored to the HIV preventive information, motivation, and behavioral skills needs of Ugandan adolescents.
Specific Aim 2 : Test the intervention in a randomized controlled trial (n=500) among adolescents attending grades Secondary 1-4 (similar to US high school grades 8th -11th) at day schools in Mbarara. Our main outcome measure is the frequency of unprotected sex 6-months post-intervention. The secondary outcome will be sexual abstinence 6-months post-intervention. We determine intervention efficacy by testing for a significant difference in outcomes between intervention and control group in an intent-to-treat analysis. This project has the potential to develop low-cost and scalable interventions to HIV transmission risk behaviors among adolescents in Uganda.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH080662-05
Application #
8115841
Study Section
Behavioral and Social Science Approaches to Preventing HIV/AIDS Study Section (BSPH)
Program Officer
Pequegnat, Willo
Project Start
2007-09-17
Project End
2012-07-31
Budget Start
2011-08-01
Budget End
2012-07-31
Support Year
5
Fiscal Year
2011
Total Cost
$174,615
Indirect Cost
Name
Center for Innovative Public Health Research
Department
Type
DUNS #
137263013
City
San Clemente
State
CA
Country
United States
Zip Code
92672
Ybarra, Michele L; Korchmaros, Josephine D; Prescott, Tonya L et al. (2015) A Randomized Controlled Trial to Increase HIV Preventive Information, Motivation, and Behavioral Skills in Ugandan Adolescents. Ann Behav Med 49:473-85
Ybarra, Michele L; Bull, Sheana S; Prescott, Tonya L et al. (2014) Acceptability and feasibility of CyberSenga: an Internet-based HIV-prevention program for adolescents in Mbarara, Uganda. AIDS Care 26:441-7
Ybarra, Michele L; Bull, Sheana S; Prescott, Tonya L et al. (2013) Adolescent abstinence and unprotected sex in CyberSenga, an Internet-based HIV prevention program: randomized clinical trial of efficacy. PLoS One 8:e70083
Katz, Ingrid T; Ybarra, Michele L; Wyatt, Monique A et al. (2013) Socio-cultural and economic antecedents of adolescent sexual decision-making and HIV-risk in rural Uganda. AIDS Care 25:258-64
Ybarra, Michele L; Korchmaros, Josephine; Kiwanuka, Julius et al. (2013) Examining the applicability of the IMB model in predicting condom use among sexually active secondary school students in Mbarara, Uganda. AIDS Behav 17:1116-28
Korchmaros, Josephine D; Ybarra, Michele L; Langhinrichsen-Rohling, Jennifer et al. (2013) Perpetration of teen dating violence in a networked society. Cyberpsychol Behav Soc Netw 16:561-7
Ybarra, Michele L; Biringi, Ruth; Prescott, Tonya et al. (2012) Usability and navigability of an HIV/AIDS internet intervention for adolescents in a resource-limited setting. Comput Inform Nurs 30:587-95; quiz 596-7
Ybarra, Michele L; Bull, Sheana S; Kiwanuka, Julius et al. (2012) Prevalence rates of sexual coercion victimization and perpetration among Uganda adolescents. AIDS Care 24:1392-400
Mitchell, Kimberly J; Bull, Sheana; Kiwanuka, Julius et al. (2011) Cell phone usage among adolescents in Uganda: acceptability for relaying health information. Health Educ Res 26:770-81
Bull, Sheana; Nabembezi, Dennis; Birungi, Ruth et al. (2010) Cyber-Senga: Ugandan youth preferences for content in an internet-delivered comprehensive sexuality education programme. East Afr J Public Health 7:58-63