HIV/AIDS is a major contributor to morbidity and mortality in Uganda. Despite aggressive advances in HIV prevention efforts, recent data suggest that HIV prevalence is increasing generally, and HIV knowledge, a direct contributor to behavior, is on the decline among young people specifically as compared to a decade ago. The Internet is a promising mode of intervention delivery in resource poor-settings because the costs associated with scaling up are minimal; dissemination online is the same if one person or 100,000 people use the program. Just as important, it provides access to important health information in a stigma-free, anonymous atmosphere. Our recent data indicate that 45% of adolescents in Mbarara, Uganda have used the Internet, 78% of whom went online at least once in the previous week. Eighty-one percent of respondents in the same survey indicated they would go to an HIV prevention web site if it existed. Based upon these data, we propose to develop a culturally appropriate, Internet-based HIV prevention program designed specifically for Ugandan adolescents between the ages of 12 and 18 years.
Our specific aims are as follows:
Specific Aim 1 : Design a 6-hour, Internet-based HIV prevention program for adolescents. Content will be culturally tailored to the HIV preventive information, motivation, and behavioral skills needs of Ugandan adolescents.
Specific Aim 2 : Test the intervention in a randomized controlled trial (n=500) among adolescents attending grades Secondary 1-4 (similar to US high school grades 8th -11th) at day schools in Mbarara. Our main outcome measure is the frequency of unprotected sex 6-months post-intervention. The secondary outcome will be sexual abstinence 6-months post-intervention. We determine intervention efficacy by testing for a significant difference in outcomes between intervention and control group in an intent-to-treat analysis. This project has the potential to develop low-cost and scalable interventions to HIV transmission risk behaviors among adolescents in Uganda. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
1R01MH080662-01A1
Application #
7339192
Study Section
Behavioral and Social Science Approaches to Preventing HIV/AIDS Study Section (BSPH)
Program Officer
Pequegnat, Willo
Project Start
2007-09-17
Project End
2012-07-31
Budget Start
2007-09-17
Budget End
2008-07-31
Support Year
1
Fiscal Year
2007
Total Cost
$552,441
Indirect Cost
Name
Center for Innovative Public Health Research
Department
Type
DUNS #
137263013
City
San Clemente
State
CA
Country
United States
Zip Code
92672
Ybarra, Michele L; Korchmaros, Josephine D; Prescott, Tonya L et al. (2015) A Randomized Controlled Trial to Increase HIV Preventive Information, Motivation, and Behavioral Skills in Ugandan Adolescents. Ann Behav Med 49:473-85
Ybarra, Michele L; Bull, Sheana S; Prescott, Tonya L et al. (2014) Acceptability and feasibility of CyberSenga: an Internet-based HIV-prevention program for adolescents in Mbarara, Uganda. AIDS Care 26:441-7
Ybarra, Michele L; Bull, Sheana S; Prescott, Tonya L et al. (2013) Adolescent abstinence and unprotected sex in CyberSenga, an Internet-based HIV prevention program: randomized clinical trial of efficacy. PLoS One 8:e70083
Katz, Ingrid T; Ybarra, Michele L; Wyatt, Monique A et al. (2013) Socio-cultural and economic antecedents of adolescent sexual decision-making and HIV-risk in rural Uganda. AIDS Care 25:258-64
Ybarra, Michele L; Korchmaros, Josephine; Kiwanuka, Julius et al. (2013) Examining the applicability of the IMB model in predicting condom use among sexually active secondary school students in Mbarara, Uganda. AIDS Behav 17:1116-28
Korchmaros, Josephine D; Ybarra, Michele L; Langhinrichsen-Rohling, Jennifer et al. (2013) Perpetration of teen dating violence in a networked society. Cyberpsychol Behav Soc Netw 16:561-7
Ybarra, Michele L; Biringi, Ruth; Prescott, Tonya et al. (2012) Usability and navigability of an HIV/AIDS internet intervention for adolescents in a resource-limited setting. Comput Inform Nurs 30:587-95; quiz 596-7
Ybarra, Michele L; Bull, Sheana S; Kiwanuka, Julius et al. (2012) Prevalence rates of sexual coercion victimization and perpetration among Uganda adolescents. AIDS Care 24:1392-400
Mitchell, Kimberly J; Bull, Sheana; Kiwanuka, Julius et al. (2011) Cell phone usage among adolescents in Uganda: acceptability for relaying health information. Health Educ Res 26:770-81
Bull, Sheana; Nabembezi, Dennis; Birungi, Ruth et al. (2010) Cyber-Senga: Ugandan youth preferences for content in an internet-delivered comprehensive sexuality education programme. East Afr J Public Health 7:58-63