Daily oral pre-exposure prophylaxis (PrEP) is effective in preventing HIV infection. However, PrEP uptake across at-risk populations including men who have sex with men (MSM) may be limited by out-of- pocket costs. Out-of-pocket costs include copays, coinsurance, and deductibles and may be a significant barrier to PrEP initiation and retention even among insured individuals. Despite being a commonly reported barrier to care, little is known about the impact of out-of-pocket costs on PrEP uptake. We propose a mixed methods and modeling study to determine the maximum out-of-pocket costs for optimal PrEP uptake in different populations including Black/African American and Hispanic/Latino MSM.
The specific aims of the proposed study are to: 1) conduct 45 semi-structured interviews with MSM to explore how out-of-pocket costs may impact PrEP uptake; and 2) model the impact of co-pays, coinsurance, and deductibles on PrEP uptake. Findings from this pilot study will inform future development of interventions that address cost as a barrier to PrEP uptake, and ultimately improve outcomes in populations at highest risk for HIV acquisition. This study aligns with the high priority topic of identifying gaps in the PrEP care continuum and associated determinants of health, and reducing racial/ethnic disparities in PrEP uptake and use as defined by the NIH and Office of AIDS Research.

Public Health Relevance

Although pre-exposure prophylaxis (PrEP) is effective in preventing HIV, high out-of-pocket costs (i.e., co-pays, deductibles, and co-insurance) may prohibit uptake of the intervention. This study evaluates the extent to which out-of-pocket costs may limit PrEP uptake. The results of this study will provide insight for public health programs as well as for development of future interventions that address cost as a barrier to PrEP uptake.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Exploratory/Developmental Grants (R21)
Project #
1R21MH118019-01
Application #
9619441
Study Section
Behavioral and Social Science Approaches to Preventing HIV/AIDS Study Section (BSPH)
Program Officer
Stirratt, Michael J
Project Start
2018-12-05
Project End
2020-11-30
Budget Start
2018-12-05
Budget End
2019-11-30
Support Year
1
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Miriam Hospital
Department
Type
DUNS #
063902704
City
Providence
State
RI
Country
United States
Zip Code