The proposed research is designed to identify risk factors associated with specific adverse outcomes in childhood and adolescence. While there are several decades worth of literature examining major depressive disorder in parents as a risk factor for offspring maladjustment, an extensive review of the literature failed to produce any research comparing parents with double depression, pure dysthymic disorder, and major depressive disorder on their children's rates of psychiatric illness and social functioning. The proposed research is designed to address this gap. More specifically, the aims of this project are to compare outpatients with DSM-IV early-onset dysthymic disorder with concurrent major depressive disorder (double depression), DSM-IV early-onset dysthymic disorder without a concurrent major depressive disorder (pure dysthymic disorder), DSM-IV episodic major depressive disorder, and normal controls with no history of Axis I disorder on the following: 1) social functioning; 2) bonding with their children; 3) marital adjustment; 4) rates of psychopathology in their offspring; and 5) social functioning in their offspring. Participants will include 40 subjects in each group. The parent groups will be compared on both interview and self-report measures of social functioning. In addition, the offspring of the four groups will be compared on rates of psychopathology, as determined by a team-consensus method, and on social functioning. Offspring adjustment will be assessed blind to the diagnostic status of the parents. Mood disorders represent a significant public health problem in the United States. Research contributing to our understanding of double depression and pure dysthymic disorder in parents and offspring maladjustment will enable us to identify children at risk and to develop effective intervention programs.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Resource-Related Research Projects (R24)
Project #
2R24MH049747-09A1
Application #
6992770
Study Section
Special Emphasis Panel (ZMH1-NRB-Q (02))
Project Start
2004-09-27
Project End
2009-05-31
Budget Start
2004-09-27
Budget End
2005-05-31
Support Year
9
Fiscal Year
2004
Total Cost
$90,654
Indirect Cost
Name
Herbert H. Lehman College
Department
Type
DUNS #
620128301
City
New York
State
NY
Country
United States
Zip Code
10468
Solessio, Eduardo; Scheraga, David; Engbretson, Gustav A et al. (2004) Circadian modulation of temporal properties of the rod pathway in larval Xenopus. J Neurophysiol 92:2672-84
Jia, Gisela (2003) The acquisition of the English plural morpheme by native Mandarin Chinese-speaking children. J Speech Lang Hear Res 46:1297-311
Swartz, K B; Chen, S; Terrace, H S (2000) Serial learning by rhesus monkeys: II. Learning four-item lists by trial and error. J Exp Psychol Anim Behav Process 26:274-85
Prohaska, V; Brown, N R; Belli, R F (1998) Forward telescoping: the question matters. Memory 6:455-65
McDonald, J; Samuels, M; Rispoli, J (1996) A hypothesis-assessment model of categorical argument strength. Cognition 59:199-217