The primary goal of the Ponce School of Medicine (PSM) MBRS-RISE Program is to increase the competitiveness and retention of underrepresented Hispanic students participating in biomedical research in the interdisciplinary Ph.D. Program at PSM in Puerto Rico. The PSM MBRS-RISE Program will address several shortcomings of our current Ph.D. program, including a low number of applicants, high withdrawal rates, the need for more specialized graduate courses and workshops, lack of financial assistance, the need for improved mentoring in preparation for post-graduate professional plans, and the need for a formal evaluation system to monitor our graduate students and provide direction for improving the training of our students. The program proposes to accomplish these goals through enhancement of the academic, research, personal, and professional competence of our underrepresented minority students, which will better prepare them for careers in the biomedical sciences. The specific measurable objectives of the PSM RISE program are as follows: (1) to increase the quality and retention of the students in the Ph.D. program;(2) to provide continuing, new, and enhanced professional development and career skills training for PSM MBRS-RISE trainees to strengthen their future competitiveness;and (3) to conduct critical evaluation and student tracking to assess program effectiveness, track the career paths of RISE graduates, and provide feedback for improving student training. The PSM MBRS-RISE program will complement existing MBRS-SCORE and RCMI programs to significantly enhance the overall research program by providing a better trained student workforce to conduct the funded research projects and provide the momentum to create new research initiatives. The enhanced training provided by the PSM MBRS-RISE program will increase the number of Hispanic Americans doing biomedical research and encourage the growth of biomedical research in Puerto Rico. By contributing to a more culturally diverse research workforce, the program will foster biomedical research of minority health disparities.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Education Projects (R25)
Project #
Application #
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Toliver, Adolphus
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Ponce School of Medicine
Schools of Medicine
United States
Zip Code
Rivera-Rivera, Yainyrette; Vázquez-Santiago, Fabián J; Albino, Elinette et al. (2016) Impact of Depression and Inflammation on the Progression of HIV Disease. J Clin Cell Immunol 7:
Matta, Jaime; Morales, Luisa; Ortiz, Carmen et al. (2016) Estrogen Receptor Expression Is Associated with DNA Repair Capacity in Breast Cancer. PLoS One 11:e0152422
de Jesus, Edelmarie Rivera; Isidro, Raymond A; Cruz, Myrella L et al. (2016) Adoptive Transfer of Dendritic Cells Expressing Fas Ligand Modulates Intestinal Inflammation in a Model of Inflammatory Bowel Disease. J Clin Cell Immunol 7:
Ortiz, Carmen; Morales, Luisa; Sastre, Miguel et al. (2016) Cytotoxicity and Genotoxicity Assessment of Sandalwood Essential Oil in Human Breast Cell Lines MCF-7 and MCF-10A. Evid Based Complement Alternat Med 2016:3696232
Torres-Reverón, Annelyn; Palermo, Karylane; Hernández-López, Anixa et al. (2016) Endometriosis Is Associated With a Shift in MU Opioid and NMDA Receptor Expression in the Brain Periaqueductal Gray. Reprod Sci 23:1158-67
Abreu-Delgado, Yamilka; Isidro, Raymond A; Torres, Esther A et al. (2016) Serum vitamin D and colonic vitamin D receptor in inflammatory bowel disease. World J Gastroenterol 22:3581-91
Encarnación, Jarline; Ortiz, Carmen; Vergne, Ralphdy et al. (2016) High DRC Levels Are Associated with Let-7b Overexpression in Women with Breast Cancer. Int J Mol Sci 17:
Isidro, Raymond A; Appleyard, Caroline B (2016) Colonic macrophage polarization in homeostasis, inflammation, and cancer. Am J Physiol Gastrointest Liver Physiol 311:G59-73
Soler-Cedeño, Omar; Cruz, Emmanuel; Criado-Marrero, Marangelie et al. (2016) Contextual fear conditioning depresses infralimbic excitability. Neurobiol Learn Mem 130:77-82
Isidro, Raymond A; Isidro, Angel A; Cruz, Myrella L et al. (2015) Double immunofluorescent staining of rat macrophages in formalin-fixed paraffin-embedded tissue using two monoclonal mouse antibodies. Histochem Cell Biol 144:613-21

Showing the most recent 10 out of 45 publications