Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37HL042846-16
Application #
6738751
Study Section
Special Emphasis Panel (NSS)
Program Officer
Ganguly, Pankaj
Project Start
1996-09-01
Project End
2009-08-31
Budget Start
2004-09-15
Budget End
2005-08-31
Support Year
16
Fiscal Year
2004
Total Cost
$511,739
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
781613492
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Moccetti, Federico; Brown, Eran; Xie, Aris et al. (2018) Myocardial Infarction Produces Sustained Proinflammatory Endothelial Activation in Remote Arteries. J Am Coll Cardiol 72:1015-1026
Shim, Chi Young; Liu, Ya Ni; Atkinson, Tamara et al. (2015) Molecular Imaging of Platelet-Endothelial Interactions and Endothelial von Willebrand Factor in Early and Mid-Stage Atherosclerosis. Circ Cardiovasc Imaging 8:e002765
Kaplan, Zane S; Zarpellon, Alessandro; Alwis, Imala et al. (2015) Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4. Nat Commun 6:7835
Guidotti, Luca G; Inverso, Donato; Sironi, Laura et al. (2015) Immunosurveillance of the liver by intravascular effector CD8(+) T cells. Cell 161:486-500
Koltsova, E K; Sundd, P; Zarpellon, A et al. (2014) Genetic deletion of platelet glycoprotein Ib alpha but not its extracellular domain protects from atherosclerosis. Thromb Haemost 112:1252-63
Yokota, N; Zarpellon, A; Chakrabarty, S et al. (2014) Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice. J Thromb Haemost 12:71-81
Baccala, Roberto; Welch, Megan J; Gonzalez-Quintial, Rosana et al. (2014) Type I interferon is a therapeutic target for virus-induced lethal vascular damage. Proc Natl Acad Sci U S A 111:8925-30
Doshi, Nishit; Orje, Jennifer N; Molins, Blanca et al. (2012) Platelet mimetic particles for targeting thrombi in flowing blood. Adv Mater 24:3864-9
Li, Conglei; Piran, Siavash; Chen, Pingguo et al. (2011) The maternal immune response to fetal platelet GPIb* causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies. J Clin Invest 121:4537-47
Zarpellon, Alessandro; Celikel, Reha; Roberts, James R et al. (2011) Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I. Proc Natl Acad Sci U S A 108:8628-33

Showing the most recent 10 out of 77 publications