The purpose of this program is to provide promising young scientists with mentor-based training in a dynamic, highly collaborative and interactive environment to promote their development as independent investigators engaged in alcohol research. Highly qualified candidates are competitively selected from a large applicant pool recruited through advertisements in addiction- and neuroscience-related societies and publications, referrals from established colleagues in the field of alcohol research, and from letters of inquiry resulting from the Training Faculty?s publications and public presentations. Mechanisms are in place to encourage applications from underrepresented groups, to foster diversity in the training program and the field of addiction research. A rigorous training program has been established to develop trainees? skills in (i) identifying important, relevant and testable hypotheses, (ii) experimental design and conduct, (iii) data analysis and interpretation, and (iv) scientific communication through written and oral presentation. Emphasis is placed on career development, and trainees complete an Individual Development Plan (IDP) upon admission to the program to generate trainee-mentor discussions of career plans and goals, strategies and timelines for achieving these goals, and ways in which these goals may have changed during the training period. Trainees are encouraged to engage in numerous workshops and resources available at The Scripps Research Institute (TSRI) on effective CV development, networking, job applications and interviewing techniques. In addition, mentors and Program Faculty actively engage trainees in discussions of each of these skills on an ongoing basis. Throughout their tenure in the program, trainees are educated in the responsible conduct of research, and this occurs via courses offered through the TSRI Career and Postdoctoral Services Office, the annual Neuropsychopharmacology of Addiction course taught by the Program Faculty, and through day-to-day input from mentors and Program Faculty regarding ethical practices in laboratory research. The highly collaborative group of 16 Program Faculty members is characterized by strong, well-funded programs in alcohol and addiction research incorporating multidisciplinary experimental approaches combining biochemical, morphological, physiological, and behavioral techniques. This is a translational training program associated with the longstanding TSRI P60 Alcohol Research Center, and trainees can engage in studies spanning the molecular and cellular domains, through investigations of neurobiological mechanism in whole animals, and clinical studies in humans on the vulnerability to alcoholism, and the development of therapeutics for this prevalent disorder. The training program has functioned continuously since 1979 under three successive Program Directors, and has a consistent record of preparing outstanding young investigators for a rapid transition to independent and impactful careers in alcohol research and addiction neuroscience.
This is a training program to train promising young scientists at the postdoctoral level (post Ph.D.) in molecular, cellular, behavioral and clinical neuropsychopharmacology. Trainees participate in scientific project development, seminars from visiting scientists, a course in neuropsychopharmacology, a course in ethical conduct of research, and training in career development for pathways to independence. Established procedures for recruitment, evaluation and career development are in place. !
|Kreisler, A D; Mattock, M; Zorrilla, E P (2018) The duration of intermittent access to preferred sucrose-rich food affects binge-like intake, fat accumulation, and fasting glucose in male rats. Appetite 130:59-69|
|Varodayan, F P; Khom, S; Patel, R R et al. (2018) Role of TLR4 in the Modulation of Central Amygdala GABA Transmission by CRF Following Restraint Stress. Alcohol Alcohol 53:642-649|
|Berger, Anthony L; Henricks, Angela M; Lugo, Janelle M et al. (2018) The Lateral Habenula Directs Coping Styles Under Conditions of Stress via Recruitment of the Endocannabinoid System. Biol Psychiatry 84:611-623|
|Varodayan, Florence P; Sidhu, Harpreet; Kreifeldt, Max et al. (2018) Morphological and functional evidence of increased excitatory signaling in the prelimbic cortex during ethanol withdrawal. Neuropharmacology 133:470-480|
|Sidhu, Harpreet; Kreifeldt, Max; Contet, Candice (2018) Affective Disturbances During Withdrawal from Chronic Intermittent Ethanol Inhalation in C57BL/6J and DBA/2J Male Mice. Alcohol Clin Exp Res 42:1281-1290|
|Spierling, Samantha R; Kreisler, Alison D; Williams, Casey A et al. (2018) Intermittent, extended access to preferred food leads to escalated food reinforcement and cyclic whole-body metabolism in rats: Sex differences and individual vulnerability. Physiol Behav 192:3-16|
|Kirson, Dean; Oleata, Christopher Shaun; Parsons, Loren Howell et al. (2018) CB1 and ethanol effects on glutamatergic transmission in the central amygdala of male and female msP and Wistar rats. Addict Biol 23:676-688|
|Natividad, Luis A; Steinman, Michael Q; Laredo, Sarah A et al. (2017) Phosphorylation of calcium/calmodulin-dependent protein kinase II in the rat dorsal medial prefrontal cortex is associated with alcohol-induced cognitive inflexibility. Addict Biol :|
|Kimbrough, Adam; Kim, Sarah; Cole, Maury et al. (2017) Intermittent Access to Ethanol Drinking Facilitates the Transition to Excessive Drinking After Chronic Intermittent Ethanol Vapor Exposure. Alcohol Clin Exp Res 41:1502-1509|
|Schmeichel, Brooke E; Herman, Melissa A; Roberto, Marisa et al. (2017) Hypocretin Neurotransmission Within the Central Amygdala Mediates Escalated Cocaine Self-administration and Stress-Induced Reinstatement in Rats. Biol Psychiatry 81:606-615|
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