The intersection of genomics and infectious diseases has defined one of the most important leading edges in contemporary science and one of the most critical areas of advancement in medicine, and as a result, has provided a rich intellectual foundation for the training of postdoctoral scholars in infectious diseases. The objectives of the grant are to train M.D. and Ph.D. post-doctoral fellows in the application of genomics to infectious diseases, and to prepare them for successful, productive, independent careers that have a significant impact on the health-related research needs of the nation. We propose to prepare all trainees- irrespective of whether they intend to conduct their research at the bench or from the bedside, in fundamentals of both genomics and applied clinical investigation, with the goal of enhancing the translation of scientific discoveries into clinical practice. We request support for five postdoctoral fellows each year. Ph.D. candidates who have completed their thesis work and M.D. candidates who have completed their clinical training will be evaluated by the Program's Steering Committee and offered admission on the basis of exceptional academic record, faculty interviews, and interest in, and aptitude for research. Every effort will be made to attract minority candidates. The training program will be interdisciplinary, involving faculty from Applied Physics, Biology, Biochemistry, Bioengineering, Chemical Engineering, Chemistry, Emergency Medicine, Genetics, Health Research and Policy, Medicine, Microbiology & Immunology, Pathology, and Pediatrics. All fellows will train for at least two years. Each trainee will be encouraged to take courses in clinical research and in basic sciences related to genomics. Additionally, each trainee will complete a two- year interdisciplinary core curriculum in applied genomics of infectious diseases. Beginning in the first year, each fellow will embark on an in-depth research project supervised by one or more of the Program's faculty; in many cases, joint-mentoring will involve faculty from different disciplines. In this way, many research projects will be cross-disciplinary. Seminars by trainees and an annual research retreat will promote interactions between program participants. While support from the Training grant will be for one year, a minimum of two years of support is guaranteed for each trainee using funds from the faculty mentor; all fellows will be encouraged to seek independent support after the first year. The program intends to meet a recognized need for clinician-scientists in Infectious Diseases who are trained in functional and applied genomics ? a recognized strength at Stanford University School of Medicine. This training grant has been, and continues to be the primary source of postdoctoral research training support for clinician-scholars. Trainees are expected to transition to independent positions in academia or industry, or positions in public health leadership and apply their education in genomics to address pressing issues in infectious diseases.

Public Health Relevance

The objectives of the grant are to train M.D. and Ph.D. post-doctoral fellows in the application of genomics to infectious diseases, and to prepare them for successful, productive, independent careers that have a significant impact on the health-related research needs of the nation. The training program will exploit the world-class resources and leadership at the host institution in the field of genomics. Graduating trainees from this program will be unusually well-prepared to enhance the public health through the application of this powerful field of science.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
2T32AI007502-21
Application #
9149081
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Robbins, Christiane M
Project Start
1995-08-01
Project End
2021-07-31
Budget Start
2016-08-01
Budget End
2017-07-31
Support Year
21
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Stanford University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94304
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