Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI016732-06S1
Application #
3126794
Study Section
Bacteriology and Mycology Subcommittee 1 (BM)
Project Start
1981-01-01
Project End
1987-02-28
Budget Start
1987-01-01
Budget End
1987-02-28
Support Year
6
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Katzen, N A; Segal, G M; Vannier, E et al. (1992) Comparison of granulocyte-macrophage colony stimulating factor and interleukin-1 production from human peripheral blood mononuclear cells as measured by specific radioimmunoassays. Eur Cytokine Netw 3:365-72
Georgilis, K; Noring, R; Steere, A C et al. (1991) Neutrophil chemotactic factors in synovial fluids of patients with Lyme disease. Arthritis Rheum 34:770-5
Georgilis, K; Steere, A C; Klempner, M S (1991) Infectivity of Borrelia burgdorferi correlates with resistance to elimination by phagocytic cells. J Infect Dis 163:150-5
Lindler, L E; Klempner, M S; Straley, S C (1990) Yersinia pestis pH 6 antigen: genetic, biochemical, and virulence characterization of a protein involved in the pathogenesis of bubonic plague. Infect Immun 58:2569-77
Klempner, M S; Noring, R; Mier, J W et al. (1990) An acquired chemotactic defect in neutrophils from patients receiving interleukin-2 immunotherapy. N Engl J Med 322:959-65
Styrt, B; Klempner, M S (1988) Lysosomotropic amines modulate neutrophil calcium homeostasis. J Cell Physiol 135:309-16
Styrt, B; Klempner, M S (1988) Effects of pH on killing of Staphylococcus aureus and Escherichia coli by constituents of the neutrophil phagolysosome. J Med Microbiol 25:101-7
Styrt, B; Pollack, C R; Klempner, M S (1988) An abnormal calcium uptake pump in Chediak-Higashi neutrophil lysosomes. J Leukoc Biol 44:130-5
Georgilis, K; Klempner, M S (1988) In vitro effects of omega-3 fatty acids on neutrophil intracellular calcium homeostasis and receptor expression for FMLP and LTB4. Inflammation 12:475-90
Styrt, B; Klempner, M S (1988) Lysosomotropic behavior of adrenergic antagonists in interactions with human neutrophils. Biochem Pharmacol 37:435-41

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