There is a continuing and urgent need for greater understanding of virus infections and, consequently, a need for a robust virology research community in the U.S and the world. The purpose of the Virology Training Program at the University of Iowa is to train young scientists to be productive members of that research community. The Virology Training Grant at the University of Iowa helps in two ways. First, it fosters the rigorous training of PhD students in the study of virology. Second, it promotes interaction among students and faculty interested in virology across the University of Iowa. By providing stipend support and travel funds for graduate students, the Training Grant will facilitate recruitment of students interested in virology. By establishing curriculum requirements that include research and literature seminars for the virology community and the collaborative teaching of virology training courses the Training Grant will promote interaction in the larger virology community at the University of Iowa and beyond. There are ten Virology Training Grant faculty who represent a wide variety of research interests from study of very basic processes in the molecular and cellular biology of virus replication, to study of host animal responses to virus infection, to study of the most efficient mechanisms for gene delivery by viruses. We seek support for three predoctoral graduate students for two years between their second and fourth years of study.
Virus infections have critical public health relevance because: (i) They are a major cause of human disease. (ii) Their intimate relationship with host cells makes them useful tools for studying normal cellular functions. (iii) They are vehicles for gene delivery in remedial gene therapy and vaccine development. There is a need to train scientists who can meet the public health threat and exploit opportunities presented by viruses.
|Hemann, Emily A; Sjaastad, Louisa E; Langlois, Ryan A et al. (2016) Plasmacytoid Dendritic Cells Require Direct Infection To Sustain the Pulmonary Influenza A Virus-Specific CD8 T Cell Response. J Virol 90:2830-7|
|Vu, Amber; Poyzer, Chelsea; Roller, Richard (2016) Extragenic Suppression of a Mutation in Herpes Simplex Virus 1 UL34 That Affects Lamina Disruption and Nuclear Egress. J Virol 90:10738-10751|
|Moller-Tank, Sven; Maury, Wendy (2015) Ebola virus entry: a curious and complex series of events. PLoS Pathog 11:e1004731|
|Yuan, Jinxiang; Li, Ming; Torres, Yasaira Rodriguez et al. (2015) Differentiation-Coupled Induction of Human Cytomegalovirus Replication by Union of the Major Enhancer Retinoic Acid, Cyclic AMP, and NF-ÎºB Response Elements. J Virol 89:12284-98|
|Mielech, Anna M; Deng, Xufang; Chen, Yafang et al. (2015) Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis. J Virol 89:4907-17|
|Christiaansen, Allison; Varga, Steven M; Spencer, Juliet V (2015) Viral manipulation of the host immune response. Curr Opin Immunol 36:54-60|
|Lennemann, Nicholas J; Walkner, Madeline; Berkebile, Abigail R et al. (2015) The Role of Conserved N-Linked Glycans on Ebola Virus Glycoprotein 2. J Infect Dis 212 Suppl 2:S204-9|
|Moller-Tank, Sven; Albritton, Lorraine M; Rennert, Paul D et al. (2014) Characterizing functional domains for TIM-mediated enveloped virus entry. J Virol 88:6702-13|
|Lennemann, Nicholas J; Rhein, Bethany A; Ndungo, Esther et al. (2014) Comprehensive functional analysis of N-linked glycans on Ebola virus GP1. MBio 5:e00862-13|
|Gorman, Jacob V; Starbeck-Miller, Gabriel; Pham, Nhat-Long L et al. (2014) Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection. J Immunol 192:3133-42|
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