Long-term goals: Among the current portfolio of NIDA funded training grants, none have comorbidity as a primary focus. This is striking given co-occurrence prevalence of Substance Use Disorders (SUD) with other psychiatric conditions and health conditions (e.g. diabetes), and the extent to which either SUD or the comorbid disorder can go under- or untreated in conventional treatment settings. Enhancing research expertise to improve diagnostic, treatment and prevention strategies is essential. The proposed program will develop a cadre of scientists with research expertise in comorbidity mechanisms, antecedents and correlates, diagnostics, and psychosocial and pharmacological interventions. Component objectives are to provide each trainee with a working knowledge of comorbidity research including: (a) translational science from Early Phase Clinical Trials to Community Based Participatory Research perspectives;(b) effective research strategies for comorbid conditions across populations and ethnic and cultural groups (e.g. American Indian, Hmong, Somali). Accomplishing programmatic features will capitalize on (a) the spectrum of faculty expertise providing mentoring across multiple areas, and (b) integration across training programs and departments. Key Elements: (1) Involvement of scientists and clinicians with diverse expertise and a core internal advisory group. Primary sites (4 postdoctoral trainees, 2 yrs each) are the Departments of Psychiatry (UMN Twin Cities) and Biobehavioral Health &Population Science (UMN Duluth), supported by the Psychology Department (UMTC) and other UMN entities;(2) Recruitment, including under represented group outreach, of rigorously screened PhD and MD candidates with SUD and comorbidity as primary career focus;(3) Training with an interdisciplinary mentoring team (primary &2 secondary mentors) with complementary expertise;(4) Formal training plans with clear milestones including trainee development of an NIH application initiated in Year 1;(5) Active research, seminars, didactic course work, workshops, and development of management, ethics, and regulatory expertise;(6) Dynamic program administration entailing monitoring with enhancements and problem resolution along with continued contact with trainees after completion and;(7) Annually convened external advisory group. Resources: Mentor funding sources include NIH Institutes, NSF, Minnesota Medical Foundation, and pharmaceutical industry. Key Personnel and Primary Mentors are directors of clinics, centers, or departments with significant resources. The program focuses on trainee expertise in SUD co-occurring with psychiatric disorders (Anxiety, ADHD, Borderline, Eating, Depression, Schizophrenia, Trauma).
Substance use disorders (e.g. alcohol, opioids, cocaine, nicotine) are commonly associated with other psychiatric conditions (e.g. depression, schizophrenia). The disorder combinations are not well understood and are often under-treated or untreated. The problems may be exacerbated, or treatment efficacy attenuated, by individual, ethnic and cultural factors. There is a need to train researchers expert in examining determinants and developing effective prevention and treatment strategies for the combined problems and circumstances;this is the focus of the post doctoral training program.
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|Forbes, Miriam K; Eaton, Nicholas R; Krueger, Robert F (2016) Sexual Quality of Life and Aging: A Prospective Study of a Nationally Representative Sample. J Sex Res :1-12|
|Forbes, Miriam K; Tackett, Jennifer L; Markon, Kristian E et al. (2016) Beyond comorbidity: Toward a dimensional and hierarchical approach to understanding psychopathology across the life span. Dev Psychopathol 28:971-986|
|Philip, Jacques; Ford, Tara; Henry, David et al. (2016) Relationship of Social Network to Protective Factors in Suicide and Alcohol Use Disorder Intervention for Rural Yup'ik Alaska Native Youth. Interv Psicosoc 25:45-54|
|Fok, Carlotta Ching Ting; Henry, David; Allen, James (2015) Maybe Small Is Too Small a Term: Introduction to Advancing Small Sample Prevention Science. Prev Sci 16:943-9|
|Henry, David; Fok, Carlotta Ching Ting; Allen, James (2015) Why Small is Too Small a Term: Prevention Science for Health Disparities, Culturally Distinct Groups, and Community-Level Intervention. Prev Sci 16:1026-32|
|Allen, James; Mohatt, Gerald V; Beehler, Sarah et al. (2014) People awakening: collaborative research to develop cultural strategies for prevention in community intervention. Am J Community Psychol 54:100-11|
|Allen, James; Mohatt, Gerald V (2014) Introduction to ecological description of a community intervention: building prevention through collaborative field based research. Am J Community Psychol 54:83-90|
|Gonzalez, John; Trickett, Edison J (2014) Collaborative measurement development as a tool in CBPR: measurement development and adaptation within the cultures of communities. Am J Community Psychol 54:112-24|
|Allen, James; Mohatt, Gerald V; Fok, Carlotta Ching Ting et al. (2014) A protective factors model for alcohol abuse and suicide prevention among Alaska Native youth. Am J Community Psychol 54:125-39|
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