The goal of the UIC Multidisciplinary Oral Sciences Training Program (MOST Program) is to provide outstanding research training to predoctoral and postdoctoral trainees in five areas relevant to the oral craniofacial complex: microbiology/immunology, oral cancer, wound healing, tissue engineering/ biomaterials, and clinical/translational research. The MOST Program provides a comprehensive and flexible approach to training individuals, with the goal of establishing a pipeline of young scientists and clinician scientists who are expertly trained and will pursue careers in oral health research. The program consists of three components. The first component, short term predoctoral research training for dental students, offers brief training activities that will induce participants to consider careers in oral health research. The second component, long-term predoctoral training, will train DSTP students, and includes study within the COD doctoral program in Oral Sciences or an aligned doctoral program. Highly qualified non-dentists may also obtain a PhD in this component. The third component, postdoctoral training, targets individuals who already hold a PhD, DOS, or DDS-PhD, with the goal of preparing them to be fully capable independent scientists in oral health research. For post-graduates, the program will be individually tailored. Post-graduate dentists who require additional formal research training will complete either a PhD program or the MS in Clinical Research (via a UIC K30 Clinical Research Training Program). To encourage translational research, predoctoral and postdoctoral non-clinician trainees will participate in an innovative Introduction to Clinical Problems Program. All trainees will have access to training in translational research via the UIC Center for Clinical and Translational Science. Trainees from all program components will interact through scheduled journal clubs, seminars, and meetings. The program is supported by an interdisciplinary and collaborative group of 27 faculty mentors from the UIC Colleges of Dentistry, Engineering, Pharmacy, and Medicine. Each faculty member maintains an active research program within the five focus areas of research and has appropriate mentoring experience. The enrollment of under-represented minorities is fostered by an established and vibrant recruitment plan. Due to recent growth in our research capacity and infrastructure, UIC is poised to provide research training to support the NIDCR stated goal of """"""""ensuring an adequate and well trained research workforce that reflects the current and emerging needs of science and includes sufficient numbers of investigators from diverse disciplines and from underrepresented groups.""""""""

National Institute of Health (NIH)
National Institute of Dental & Craniofacial Research (NIDCR)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Special Emphasis Panel (ZDE1-MK (12))
Program Officer
King, Lynn M
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Illinois at Chicago
Schools of Dentistry
United States
Zip Code
Lagunas, Angelica M; Wu, Jianchun; Crowe, David L (2017) Telomere DNA damage signaling regulates cancer stem cell evolution, epithelial mesenchymal transition, and metastasis. Oncotarget 8:80139-80155
Kulakowski, Daniel; Leme-Kraus, Ariene A; Nam, Joo-Won et al. (2017) Oligomeric proanthocyanidins released from dentin induce regenerative dental pulp cell response. Acta Biomater 55:262-270
Simmler, Charlotte; Kulakowski, Daniel; Lankin, David C et al. (2016) Holistic Analysis Enhances the Description of Metabolic Complexity in Dietary Natural Products. Adv Nutr 7:179-89
Rice, Amy J; Lei, Hao; Santarsiero, Bernard D et al. (2016) Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase). Bioorg Med Chem 24:4536-4543
Rice, Amy J; Woo, Jerry K; Khan, Attiya et al. (2016) Over-expression, purification, and confirmation of Bacillus anthracis transcriptional regulator NprR. Protein Expr Purif 125:83-9
Hu, Xiaoyu; Jhun, Ellie H; Yao, Yingwei et al. (2016) IL1A rs1800587 associates with chronic noncrisis pain in sickle cell disease. Pharmacogenomics 17:1999-2006
Bisson, Jonathan; McAlpine, James B; Friesen, J Brent et al. (2016) Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery? J Med Chem 59:1671-90
Chastkofsky, Michael I; Bie, Wenjun; Ball-Kell, Susan M et al. (2015) Protein Tyrosine Kinase 6 Regulates UVB-Induced Signaling and Tumorigenesis in Mouse Skin. J Invest Dermatol 135:2492-2501
Padovano, J D; Ravindran, S; Snee, P T et al. (2015) DMP1-derived peptides promote remineralization of human dentin. J Dent Res 94:608-14
Wietecha, Mateusz S; Król, Mateusz J; Michalczyk, Elizabeth R et al. (2015) Pigment epithelium-derived factor as a multifunctional regulator of wound healing. Am J Physiol Heart Circ Physiol 309:H812-26

Showing the most recent 10 out of 45 publications