The Training Program in Biochemistry, Cell and Molecular Biology provides the predoctoral candidate with multidisciplinary training in the broad area of cell structure and function. The Training Faculty constitute the interdepartmental Graduate Program in Biochemistry, Cell and Developmental Biology (BCDB), one of eight interdisciplinary training programs in the Graduate Division of Biological and Biomedical Sciences (GDBBS) at Emory. The 54 Training Faculty hold their primary academic appointments in diverse departments including, Biochemistry, Biology, Cell Biology, Chemistry, Human Genetics, Medicine (Digestive Diseases, Nephrology, Pulmonary Medicine), Ophthalmology, Pathology, Pharmacology, Physiology, Surgery, and the Winship Cancer Institute. Their research programs are clustered into four main overlapping themes: biochemistry/structural biology, cancer biology, cell biology and developmental biology. Concomitant with this range of biological problems, the trainee is able to take advantage of diverse model systems and state- of-the-art technical resources. The 7 stipends support students in their second year of training, although some exceptional students are supported for a portion of their third year as well. Trainees are selected for support from the larger pool of students matriculating in the parent BCDB Program, which currently has 64 trainees. All trainees take a core curriculum that emphasizes the foundations of biochemistry, molecular biology, biophysics, cell biology, genetics and developmental biology. Additional courses in scientific writing, seminar presentation, and ethics are also required. Advanced electives are available in the full range of biomedical disciplines to give the student in-depth and individualized preparation for their research careers. The training environment is enriched by the BCMB-sponsored, trainee-organized annual Symposium, weekly journal clubs and seminars. The successful graduate will be well suited, after appropriate postdoctoral training, to pursue an independent research career. In this regard, most graduates have moved on to top tier postdoctoral positions, and some now hold tenure-track, or tenured, positions in top academic institutions.

Public Health Relevance

Research conducted by trainees, under the supervision of their mentors, impact a wide range of public health related issues. Projects focus on aspects of congenital malformations, inherited diseases, degenerative diseases, as well as cancer.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008367-25
Application #
8690865
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Gindhart, Joseph G
Project Start
1990-07-01
Project End
2015-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
25
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Emory University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Schlingmann, Barbara; Overgaard, Christian E; Molina, Samuel A et al. (2016) Regulation of claudin/zonula occludens-1 complexes by hetero-claudin interactions. Nat Commun 7:12276
Schureck, Marc A; Repack, Adrienne; Miles, Stacey J et al. (2016) Mechanism of endonuclease cleavage by the HigB toxin. Nucleic Acids Res 44:7944-53
Li, Wenqi; Allen, Megan E; Rui, Yanfang et al. (2016) p39 Is Responsible for Increasing Cdk5 Activity during Postnatal Neuron Differentiation and Governs Neuronal Network Formation and Epileptic Responses. J Neurosci 36:11283-11294
Barron, Daniel A; Moberg, Kenneth (2016) Inverse regulation of two classic Hippo pathway target genes in Drosophila by the dimerization hub protein Ctp. Sci Rep 6:22726
Wigington, Callie P; Morris, Kevin J; Newman, Laura E et al. (2016) The Polyadenosine RNA-binding Protein, Zinc Finger Cys3His Protein 14 (ZC3H14), Regulates the Pre-mRNA Processing of a Key ATP Synthase Subunit mRNA. J Biol Chem 291:22442-22459
Kelly, Seth M; Bienkowski, Rick; Banerjee, Ayan et al. (2016) The Drosophila ortholog of the Zc3h14 RNA binding protein acts within neurons to pattern axon projection in the developing brain. Dev Neurobiol 76:93-106
Whitlock, Jarred M; Hartzell, H Criss (2016) A Pore Idea: the ion conduction pathway of TMEM16/ANO proteins is composed partly of lipid. Pflugers Arch 468:455-73
Wasson, Jadiel A; Simon, Ashley K; Myrick, Dexter A et al. (2016) Maternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally. Elife 5:
Williams, Kathryn R; McAninch, Damian S; Stefanovic, Snezana et al. (2016) hnRNP-Q1 represses nascent axon growth in cortical neurons by inhibiting Gap-43 mRNA translation. Mol Biol Cell 27:518-34
Hwang, Juyeon; Lee, Jocelyn A; Pallas, David C (2016) Leucine Carboxyl Methyltransferase 1 (LCMT-1) Methylates Protein Phosphatase 4 (PP4) and Protein Phosphatase 6 (PP6) and Differentially Regulates the Stable Formation of Different PP4 Holoenzymes. J Biol Chem 291:21008-21019

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