Biostatistics plays a fundamental role in medical, biomedical and public health research. Advances in medical technology alone have substantially increased the demand for trained biostatisticians to demonstrate basic scientific knowledge, effectiveness and feasibility. There is a growing need for biostatisticians to be trained in a broad range of fields, including the biological sciences, quantitative sciences and clinical applications. Researchers in the medical and life sciences are expressing a growing need for applied biostatisticians who are trained with a background in biology and strong communication skills as well as quantitative skills. Most applied biostatisticians function in collaborative environments that require interdisciplinary knowledge and strong communication skills, but many do not receive training in biology and bioinformatics. Not only do biostatisticians need to be trained how to apply the wide range of quantitative methods that are needed in biomedical research, but they also need an understanding of the biological basis for disease and the biological measures that are collected in biomedical research. The goal of this training grant proposal is to seek continued funding for our training program for pre-doctoral students in biostatistics that provides a strong background in quantitative skills, biology, applied research and exposure to the proper conduct of ethical research. Our program of 1-3 years includes course work required of all biostatistics doctoral students along with rotations in bioinformatics, genetics, ethical conduct of research, observational studies and clinical trials. In the rotations students work on an applied research project gaining important experience in an environment that provides excellent experience in interdisciplinary research. This program produces students not only with classroom exposure to quantitative skills, but also practical experience as a functioning biostatistician.

Public Health Relevance

The NIH has identified a growing need to educate biostatisticians through an interdisciplinary approach. Additionally, there is a growing need to include minorities and disabled persons in this important field. This program plays an important role in addressing both needs within the United States.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Gaillard, Shawn R
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Boston University
Biostatistics & Other Math Sci
Schools of Public Health
United States
Zip Code
Burke, Gordon M; Genuardi, Michael; Shappell, Heather et al. (2017) Temporal Associations Between Smoking and Cardiovascular Disease, 1971 to 2006 (from the Framingham Heart Study). Am J Cardiol 120:1787-1791
Ferencik, Maros; Pencina, Karol M; Liu, Ting et al. (2017) Coronary Artery Calcium Distribution Is an Independent Predictor of Incident Major Coronary Heart Disease Events: Results From the Framingham Heart Study. Circ Cardiovasc Imaging 10:
Jones-López, Edward C; Acuña-Villaorduña, Carlos; Fregona, Geisa et al. (2017) Incident Mycobacterium tuberculosis infection in household contacts of infectious tuberculosis patients in Brazil. BMC Infect Dis 17:576
Niiranen, Teemu J; Larson, Martin G; McCabe, Elizabeth L et al. (2017) Prognosis of Prehypertension Without Progression to Hypertension. Circulation 136:1262-1264
Niiranen, Teemu J; McCabe, Elizabeth L; Larson, Martin G et al. (2017) Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study. BMJ 357:j1949
McIntosh, Avery I; Doros, Gheorghe; Jones-López, Edward C et al. (2017) Extensions to Bayesian generalized linear mixed effects models for household tuberculosis transmission. Stat Med 36:2522-2532
Mayinger, Michael Christian; Merchant-Borna, Kian; Hufschmidt, Jakob et al. (2017) White matter alterations in college football players: a longitudinal diffusion tensor imaging study. Brain Imaging Behav :
Baltrusaitis, Kristin; Santillana, Mauricio; Crawley, Adam W et al. (2017) Determinants of Participants' Follow-Up and Characterization of Representativeness in Flu Near You, A Participatory Disease Surveillance System. JMIR Public Health Surveill 3:e18
Bell, Vanessa; McCabe, Elizabeth L; Larson, Martin G et al. (2017) Relations Between Aortic Stiffness and Left Ventricular Mechanical Function in the Community. J Am Heart Assoc 6:
Justice, Anne E (see original citation for additional authors) (2017) Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. Nat Commun 8:14977

Showing the most recent 10 out of 40 publications